Fluoroquinolone-3-carboxamide amino acid conjugates: Synthesis, antibacterial properties and molecular modeling studies.
CONCLUSION: The observed antibacterial experimental data indicates the selectivity of our synthesized conjugates against E.Coli. The protecting group on amino acids decreases the antibacterial activity. The synthesized conjugates are non-toxic to the normal cell lines. The experimental data were supported by computational studies.
PMID: 31483233 [PubMed - as supplied by publisher]
Source: Medicinal Chemistry - Category: Chemistry Authors: Bokhtia RM, Panda SS, Girgis AS, Honkanadavar HH, Ibrahim TS, Al-Mahmoudy AMM, George RF, Kashef MT, Fayad W, Sakhuja R, Abdel-Aal EH Tags: Med Chem Source Type: research
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