House Dust Mite-Induced Allergic Rhinitis: Is Prevention an Option?

AbstractPurpose of reviewThe aim of this paper is to review and summarise the current knowledge of prevention of house dust mite (HDM)-induced allergic rhinitis (AR).Recent findingsAR can be either classified as seasonal/intermittent (for example hay fever occurring summer and autumn) or perennial/persistent (occurring throughout the year). The commonest trigger for seasonal AR is pollen whereas HDMs are the key allergic trigger for perennial AR. HDMs are a recognised indoor allergen that is crucial in the development of AR, asthma, and atopic dermatitis.SummaryPreventive strategies have gained acceptance for the management scheme in the treatment of patients with AR. Specifically, preventive measures include allergen avoidance, environmental control, and immunotherapy. The primary goal of medical treatment is to reduce the burden of disease, improve quality of life and to prevent the development of the sequelae of AR such as bronchial asthma. Prevention is a viable option and key component in HDM-AR management. As urbanisation and lifestyle changes lead to the increase of HDM-AR, there should be a more concerted effort towards prevention.
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research

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Biologics have revolutionized medical therapy in the past 2 decades. Allergic Diseases have benefited from this revolution as a variety of biologics have impacted all categories of allergic diseases. Anticytokines directed at type 2 immunity has helped in the treatment of all allergic conditions covered in this issue ranging from Allergic Rhinitis to Asthma to Atopic Dermatitis to Food Allergy and others. Obviously, the ravages of COVID-19 on processes involved in biologic treatment are a consideration, but current thinking suggests such therapies should not be affected by the pandemic.
Source: Immunology and Allergy Clinics of North America - Category: Allergy & Immunology Authors: Tags: Preface Source Type: research
CONCLUSION: Atopic disorders, previously recognized as predictors of poor sleep, are associated with COPCs after accounting for sleep problems. PMID: 32975542 [PubMed - as supplied by publisher]
Source: Journal of Orofacial Pain - Category: ENT & OMF Tags: J Oral Facial Pain Headache Source Type: research
Discussion There are 8 common foods which compromise 90% of food allergens with those being peanuts, soybeans, cow’s milk, eggs, fish, crustacean/shellfish, wheat and tree nuts. Some people believe that lupin (a legume) is 9th. Legumes belong to the Fabaceae family. They provide protein, fat, vitamins other essential nutrients and therefore are used in the human diet throughout the world. “[A]llergenicity due to consumption of legumes in decreasing order may be peanut, soybean, lentil, chickpea, pea, mung bean and red gram.” Other common legumes include alfalfa, clovers, beans, lupins, mesquite, carob...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Authors: Won JY, Kwon JW, Hong SN, Lee WH Abstract Background: The association between pet sensitization and pet ownership remains unclear. We elucidated the association between pet sensitization and pet ownership by age. Methods: We retrospectively reviewed 2883 patients who visited our allergy clinic for nasal symptoms from January 2003 to December 2014; 1957 patients with data on skin-prick tests and questionnaire responses were included, and divided into adult (age>19) and children (≤19) groups; the association between pet sensitization and pet ownership was evaluated in both groups. Results: Amon...
Source: Clinical and Experimental Otorhinolaryngology - Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research
Allergic diseases represent some of the most chronic and costly chronic conditions. Medical management may require long-term pharmacotherapy, which is often associated with poor adherence. Although medications provide symptomatic control, they do not modify the allergic disease. Patients may prefer disease-modifying treatments that provide lasting benefits after discontinuation. To date, allergy immunotherapy is the only proved disease modification therapy associated with lasting benefits after discontinuation. However, allergy immunotherapy safety and efficacy has only been established in allergic rhinitis, mild to modera...
Source: Immunology and Allergy Clinics of North America - Category: Allergy & Immunology Authors: Source Type: research
Authors: Dierick BJH, van der Molen T, Flokstra-de Blok BMJ, Muraro A, Postma MJ, Kocks JWH, van Boven JFM Abstract INTRODUCTION: Asthma, allergic rhinitis, atopic dermatitis and food allergy affect approximately 20% of the global population. Few studies describe the burden of the totality of these diseases and only a handful studies provide a comprehensive overview of the socioeconomic impact of these diseases. AREAS COVERED: For this narrative review, we searched Pubmed using selected keywords and inspected relevant references using a snowballing process. We provide an overview of the socioeconomic burden of ...
Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research
CONCLUSIONS: Food allergy or food intolerance was more common in subjects with allergic multimorbidity than in subjects diagnosed with one allergic disease or those free of allergic diseases. PMID: 32955224 [PubMed - in process]
Source: Annals of Agricultural and Environmental Medicine : AAEM - Category: Environmental Health Authors: Tags: Ann Agric Environ Med Source Type: research
(MediaSource) Researchers at National Jewish Health have determined that many allergic conditions likely start with dry, cracked skin, which leads to a chain reaction of allergic diseases known as the atopic march. It begins in infancy with atopic dermatitis and leads to food allergies, asthma and hay fever. Their latest study in The Journal of Allergy and Clinical Immunology: In Practice reveals that the time of year a baby is born may be a risk factor.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
The incidence of allergic diseases continues to rise. Cross-sectional and longitudinal studies have indicated that allergic diseases occur in a time-based order: from atopic dermatitis and food allergy in infancy to gradual development into allergic asthma and allergic rhinitis in childhood. This phenomenon is defined as the “atopic march”. Some scholars have suggested that the atopic march does not progress completely in a temporal pattern with genetic and environmental factors. Also, the mechanisms underlying the atopic march are incompletely understood. Nevertheless, the concept of the atopic march provides ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Atopic dermatitis (AD) is a chronic inflammatory skin disease that has been of great interest to the practicing allergists because, in childhood, it is recognized as the first step in the atopic march that leads to food allergy, allergic rhinitis, and asthma.1 Recent advances in our understanding of the complex pathobiology of AD reveal an important role for skin barrier dysfunction, genetic variation (particularly filaggrin mutations), environmental factors, and the microbiome and immune pathway polarization.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Editorial Source Type: research
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