Magnetic resonance imaging of the cervical spinal cord in spinal muscular atrophy

ConclusionsWe showed feasibility of an advanced 3 T MRI protocol that allowed differences to be determined between patients and healthy controls, confirming the potential of this technique to assess pathological mechanisms in SMA. After further development and confirmation of findings in a larger sample, these techniques may be used to study disease course of SMA in vivo and evaluate response to survival motor neuron (SMN) augmenting therapy.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research