Extracellular Vesicles as Drug Delivery Vehicles to the Central Nervous System
This article outlines the challenges in potential EV-based therapeutic delivery.
Conclusion: It is argued that the validity of all theory should not be assumed before sufficient empirical evidence has accumulated to support its validity across contexts. However, caution is required, to avoid the consequences of an unquestioning approach to empiricism.Keywords: Pseudoscience; denialism; medical practice; medical theory; empiricism.
Conclusion: Conclusively, intervention programmes should evolve enlightenment through television, movies, and educational programs that incorporate the ill effects of discrimination and stigma so as to boost self-esteem of PLHIV.Keywords: Intervention; psychological health; poverty; pocial isolation.
Conclusion: This study has unraveled the factors that are associated with testing and counseling in institutional facilities. University students seem to seek and utilize VCT services for different reasons. It is also clear that patterns of services utilization vary from group to another as observed in the case of year of study, gender and age category.Recommendations: It is necessary for policy makers in institutions of higher learning together with those tasked with managing healthcare services in these institutions to adopt approaches that will overcome the barriers to utilization of VCT services among students. With kn...
AbstractData from repeated, national behavioural HIV surveillance was used to identify similarities and differences between young gay and bisexual men (YGBM) aged 16 –24 (n = 1608) and older GBM aged 25–49 (n = 6266), in order to quantify risks and identify gaps in HIV prevention. Trend analyses from 2014 to 2018 are also reported. While there were similar rates of condomless anal intercourse with casual partners in both age groups, YGBM had lower ra tes of HIV testing and PrEP use but also fewer male partners. Our results suggest most YGBM have lower HIV risk than older GBM but a mi...
January 27, 2020 AIDS Research Advisory Committee MeetingAir date: 1/27/2020 1:00:00 PM
CONCLUSIONS: Mortality rates from HIV-associated meningitis in SSA are very high under routine care conditions. Better strategies are needed to reduce mortality from HIV-associated meningitis in the region. PMID: 31957332 [PubMed - in process]
American College of Physicians has endorsed two proposals being discussed by Democratic presidential candidates
In this study, wood and composite materials exhibit the same structural material morphology which performs as anisotropic material as it majorly contributes to failure. In this study, a state-of-the-art review of creep analysis and engineering design is carried out, with particular emphasis on the creep methodology of a cantilever beam. The existing theories and creep design approaches are grouped into two analysis methods, namely experimental and numerical approaches. To be more specific, the experimental works involved two main methods, namely load-based (conventional) and temperature-based (accelerated) techniques. Sele...
This study is the first to use free-text data to examine the frequency of Australian GBM’s PrEP-perceptions, highlighting the potential benefits and challenges to its promotion.