CRISPR-Based Directed Evolution for Crop Improvement.

CRISPR-Based Directed Evolution for Crop Improvement.
Trends Biotechnol. 2019 Aug 30;:
Authors: Butt H, Zaidi SS, Hassan N, Mahfouz M
Abstract
Directed evolution involves generating diverse sequence variants of a gene of interest to produce a desirable trait under selective pressure. CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR-associated protein 9) systems can be programmed to target any genomic locus and perform targeted directed evolution. Here, we discuss the opportunities and challenges of this emerging platform for targeted crop improvement.
PMID: 31477243 [PubMed - as supplied by publisher]

Source: Trends in Biotechnology - August 29, 2019 Category: Biotechnology Authors: Butt H, Zaidi SS, Hassan N, Mahfouz M Tags: Trends Biotechnol Source Type: research