055 Long-term effectiveness and safety of rituximab for the treatment of pemphigus in Chinese population

We aimed to assess the long-term effects and safety of RTX for the treatment of pemphigus in the Chinese population. In this retrospective study, 74 pemphigus patients treated with RTX from February 2008 to December 2018 and followed up were included and analyzed. Lymphoma protocol (LP, 375mg/m2 per week for 4 weeks) or rheumatoid arthritis protocol (RAP, 1000mg on the 1st and 15th day) was used as RTX protocol. The median follow-up duration was 26.1 months. CR rate was 66.2% and the median time to achieve CR was 11.0 months.

Source: Journal of Investigative Dermatology - August 31, 2019 Category: Dermatology Authors: Y. Chang, X. Chen, M. Wang, C. Zhang, X. Zhu Tags: Adaptive Immunity and Autoimmunity Source Type: research