060 Mechlorethamine-Induced Contact Dermatitis Avoidance Study (MIDAS): Preliminary Results

Mycosis fungoides cutaneous-type T-cell lymphoma (MF-CTCL) is a rare non-Hodgkin lymphoma. In patients with early stage MF-CTCL, topical chlormethine (=mechlorethamine) 0.016% w/w gel (equivalent to 0.02% chlormethine HCl) was reported safe and effective, but usage may be limited due to the development of contact dermatitis. The primary endpoint of the current study was to determine if Triamcinolone significantly reduces the development of chlormethine-induced contact dermatitis using the newly formulated 0.016% w/w gel.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Adaptive Immunity and Autoimmunity Source Type: research