089 Atopic Dermatitis Is Associated With an Increased Risk of Autoimmune Diseases: A Population-Based Cohort Study Using UK Primary Care Data

Atopic dermatitis (AD) is associated with a wide range of comorbidities, particularly allergies, but its association with nonatopic autoimmune disease is less well defined. Recent genome-wide association studies have reported shared genetic loci between AD and autoimmune diseases. In the UK, most patients with these conditions are managed in primary care, meaning general practice (GP) databases provide a rich data source for studying AD. A retrospective cohort study was undertaken to examine the association between AD and the following autoimmune diseases (rheumatoid arthritis [RA], ulcerative colitis [UC], Crohn ’s disease [CrD], coeliac disease [CD], multiple sclerosis [MS]) in adults and children in the UK from 2009-2018, using the Royal College of General Practitioners Research and Surveillance Centre database.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Clinical Research and Epidemiology Source Type: research