Scrutinising the Link between Periodontal Disease and Systemic Conditions: Does Recent Evidence Continue to Support the European Federation of Periodontology's 2012 Manifesto?

This article has critically evaluated the research published after the 9th European Workshop in Periodontology in November 2012 to ascertain whether recent research has affected the merit of the manifesto. It was found that recent research supports the manifesto regarding diabetes mellitus, cardiovascular disease and adverse pregnancy outcomes, although further high-quality randomised controlled trials are required to support the manifesto statement that "certain populations of pregnant women may benefit from periodontal therapy." Furthermore, there is now good evidence from systematic reviews for an association between periodontal disease and chronic obstructive pulmonary disease, rheumatoid arthritis, chronic kidney disease and metabolic syndrome. This may be sufficient to warrant an update to the manifesto. Causal relationships remain debatable. There is also recent emerging evidence for an association with obstructive sleep apnoea. The recent evidence investigating obesity and periodontal disease is mixed, and no new systematic studies or randomised controlled trials were found relating to cognitive impairment. PMID: 31473721 [PubMed]
Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research

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Source: International Journal of Pediatrics and Adolescent Medicine - Category: Pediatrics Source Type: research
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Publication date: October 2019Source: Pregnancy Hypertension, Volume 18Author(s): Laura A. Magee, Evelyne Rey, Elizabeth Asztalos, Eileen Hutton, Joel Singer, Michael Helewa, Terry Lee, Alexander G. Logan, Wessel Ganzevoort, Ross Welch, Jim G. Thornton, Peter von DadelszenAbstractThe international CHIPS Trial (Control of Hypertension In Pregnancy Study) enrolled 987 women with chronic (75%) or gestational (25%) hypertension. Pre-eclampsia developed in 48%; women remained on their allocated BP control and delivered an average of two weeks later. ‘Less tight’ control (target diastolic BP 100 mmHg) achieved BP t...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
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Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
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Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
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Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
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Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
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Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
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Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
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Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
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