2,2'-Biphenol/B(OH)3 Catalyst System for Nazarov Cyclization.
2,2'-Biphenol/B(OH)3 Catalyst System for Nazarov Cyclization.
Chem Pharm Bull (Tokyo). 2019;67(9):1019-1022
Authors: Sugimoto K, Oshiro M, Hada R, Matsuya Y
Abstract
A novel catalyst system-a combination of the readily available 2,2'-biphenol with the inexpensive, nontoxic, and eco-friendly B(OH)3-promoted the Nazarov cyclization of activated and inactivated divinyl ketones to afford the corresponding cyclopentenones up to 96% yield under, in a cis-selective manner. Compared with the conventional harsh conditions with hazardous reagents, user-friendly method was established with bench-stable and easy-to-handle reagents.
PMID: 31474725 [PubMed - in process]
Source: Chemical and Pharmaceutical Bulletin - Category: Drugs & Pharmacology Authors: Sugimoto K, Oshiro M, Hada R, Matsuya Y Tags: Chem Pharm Bull (Tokyo) Source Type: research
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