Co-Treatment with Sulforaphane and Nano-Metformin Molecules Accelerates Apoptosis in HER2+ Breast Cancer Cells by Inhibiting Key Molecules.

In conclusion, our data indicate that SLFN and MTFN can reduce cancer cell viability via both collaborative and differential effects and suggest that MTFN increases SLFN effectiveness by targeting common molecules/pathways downstream of HER2 and key for CSC signaling.
PMID: 31474154 [PubMed - as supplied by publisher]

Source: Nutrition and Cancer - September 1, 2019 Category: Cancer & Oncology Authors: Keshandehghan A, Nikkhah S, Tahermansouri H, Heidari-Keshel S, Gardaneh M Tags: Nutr Cancer Source Type: research