Pre-implantation kidney biopsy: value of the expertise in determining histological score and comparison with the whole organ on a series of discarded kidneys.

CONCLUSIONS: Our data suggests that the creation of a pool of specialist pathologists would improve organ utilization. Moreover, biopsies are not representative of the whole organ. As the Remuzzi score on biopsy is a major reasons for discard, a quota of transplantable kidneys may be erroneously discarded. Refinement in Remuzzi cut-offs based on expert reporting and recognition of sampling error of biopsies in correlation with clinical outcome data should be undertaken.
PMID: 31471818 [PubMed - as supplied by publisher]

Source: Journal of Nephrology - August 29, 2019 Category: Urology & Nephrology Authors: Girolami I, Gambaro G, Ghimenton C, Beccari S, Caliò A, Brunelli M, Novelli L, Boggi U, Campani D, Zaza G, Boschiero L, López JI, Martignoni G, D'Errico A, Segev D, Neil D, Eccher A Tags: J Nephrol Source Type: research