Cardiac Surgery in Patients with Opioid Use Disorder: An Analysis of 1.7 Million Surgeries

Publication date: Available online 31 August 2019Source: The Annals of Thoracic SurgeryAuthor(s): Rohan M. Shah, Sameer A. Hirji, Edward Percy, Samantha Landino, Farhang Yazdchi, Andrea Bellavia, Marc P. Pelletier, Prem S. Shekar, Tsuyoshi KanekoABSTRACTBackgroundAdverse repercussions associated with the current opioid epidemic have been documented in many surgical specialties. The extent of this problem in the cardiac surgery population, however, has not been previously characterized. We evaluated the impact of opioid use disorder (OUD) on in-hospital cardiac surgery outcomes using a large national database.MethodsUsing the National Inpatient Sample, we isolated patients undergoing coronary artery bypass grafting, valve repair or valve replacement from 2009-2014. Patients were stratified by OUD status. Multivariable analysis was performed to evaluate the association between opioid use and postoperative outcomes. Patients were further stratified by surgery type.ResultsOverall, 1,743,161 patients underwent cardiac surgery, and 6,960 patients suffered from OUD (0.4%). Mean age was 47.2 and 65.8 years among those with and without OUD, respectively. Although in-hospital mortality did not differ among these groups, OUD patients had significantly higher incidence of stroke (8.3% vs 2.8%), acute kidney injury (21.4% vs 16.2%), longer hospital stays (18 vs. 10 days) and higher hospitalization costs ($81,238 vs $58,654; all P
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

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