Fight Aging! Newsletter, September 2nd 2019
In conclusion, in the absence of obesity, visceral adipose tissue possesses a pronounced anti-inflammatory phenotype during aging which is further enhanced by exercise. Methods of Inducing Cellular Damage are Rarely Relevant to Aging, and the Details Matter https://www.fightaging.org/archives/2019/08/methods-of-inducing-cellular-damage-are-rarely-relevant-to-aging-and-the-details-matter/ One of the major challenges in aging research is determining whether or not models of cellular or organismal damage and its consequences are in any way relevant to the natural processes of aging. One can hit a brick with a hammer, but that says very little about how bricks weather over the years. One can hit the brick very carefully with the hammer in ways that produce results that look weathering-like, but can that be used to tell us anything about weathering? In cells the line between artificial and natural damage can be hard to pin down, but the fine details of the processes involved always matter. It is easy to break cells and see them become dysfunctional as a result, but hard to determine the relevance of that breakage to natural aging. Even in the example here, in which researchers are trying to achieve something very similar to the consequences of excessive oxidative damage in mitochondria that is observed in aging, it is possible to argue that the methodology used has little relevance to the actual damage of aging in its details, and therefore may not be a useful m...
This study compared stroke characteristics and poststroke care and disability between these groups.Stroke
Weight-bearing CT scans can provide new insight into foot and ankle disorders and valuable information for surgical planning.Journal of the American Academy of Orthopaedic Surgeons
Vaccines protecting against influenza, hepatitis B and rabies are less effective for obese people. As scientists develop a Covid-19 vaccine, experts say obesity could be an impediment, a sobering prospect for the US, where nearly half of all adults are obese.
SUPPLEMENTS could be used to improve the health of your heart, as well as to protect against high blood pressure symptoms and signs. Add these cheap garlic capsules to your diet to lower your risk of heart problems, including heart attacks and heart disease.
In this study, we investigated the potential effects of disocin on amyloid-β peptide (Aβ1-42) oligomers-treated HT22 cells. Aβ1-42 oligomers induced great neurotoxicity to HT22 cells as examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The results of terminal deoxynucleoitidyl transferase-mediated deoxyuridine triphosphate biotin nich end labeling (TUNEL) staining and flow cytometry indicated that Aβ1-42 oligomers led to increased apoptosis and generation of reactive oxygen species (ROS) in HT22 cells. However, dioscin could remarkably inhibit the neurotoxicity induce...
Those suffering from cancer, heart conditions, strokes, diabetes and lung disease are among the worst affected by delays to their diagnosis and care, a survey of senior doctors reveals.
University of Leeds experts found heart attack admissions dropped by 40 per cent in April and May in England. They say it may have been an 'unintended consequence' of Stay At Home' slogan.
HOW TO live longer: Long life expectancy is something we would all like to strive for. According to studies, the timing of when you eat could be just as important as what you eat. Health experts advise a new way of eating which will help burn fat, improve memory, aid in a healthier heart, reduce the risk of disease and boost longevity.
DIABETES type 2 symptoms may include feeling unusually tired, passing more urine than normal, and having cuts or wounds that take longer to heal than expected. But, you could also be at risk of high blood sugar if you notice a change to the appearance of your stools. What does your poo look like?
DEMENTIA describes a cluster of symptoms associated with ongoing brain decline. The telltale signs are subtle at first, including a self-reported problem.
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