Neuropsychiatric manifestations in celiac disease

Publication date: October 2019Source: Epilepsy &Behavior, Volume 99Author(s): Chiara Maria Trovato, Umberto Raucci, Francesco Valitutti, Monica Montuori, Maria Pia Villa, Salvatore Cucchiara, Pasquale ParisiAbstractCeliac disease (CD) is a systemic, chronic immune-mediated disorder elicited by gluten and related prolamines in genetically susceptible subjects. Main manifestations of CD involve the digestive tract; however, a growing body of evidence supports the theory that symptoms may occur in every part of the body. It is known that some patients with CD can be asymptomatic, and additionally, the incidence of “nonclassical” CD with extraintestinal presentation is apparently increasing. We aimed to perform a thorough review of existing evidence for neurological manifestations of CD, providing an up-to-date description of prevalence and examining the pathogenetic mechanisms possibly involved.Neurological presentations are rare in children but as many as 36% of adult patients present with neurological findings. With severe malnutrition after progression of CD, different vitamin deficiencies may develop. Such problems can in turn overlap with previous neurological abnormalities including ataxia, epilepsy, neuropathy, dementia, and cognitive disorders. Here, the most prevalent clinical manifestations in adults and children have been discussed in further detail.Further research is needed to achieve a complete understanding of the nervous system involvement in CD, ...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research

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CONCLUSION: In the outpatient clinic specializing in oral anticoagulation, patients add more specific beliefs about the interference of vitamin K-rich diet on coagulation, when compared to those in the general cardiology outpatient clinic. PMID: 31618372 [PubMed - in process]
Source: Revista gaucha de enfermagem EENFUFRGS - Category: Nursing Tags: Rev Gaucha Enferm Source Type: research
Journal Name: Journal of Perinatal Medicine Issue: Ahead of print
Source: Journal of Perinatal Medicine - Category: Perinatology & Neonatology Source Type: research
Publication date: Available online 16 October 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Mark B. Meyer, J. Wesley PikeAbstractCyp27b1 and Cyp24a1 are reciprocally regulated in the kidney by the key hormones PTH, FGF23, and 1,25(OH)2D3. Our recent genomic studies in mice identified a complex kidney-specific enhancer module located within the introns of adjacent Mettl1 (M1) and Mettl21b (M21) genes that mediate basal and PTH induction of Cyp27b1 as well as suppression by FGF23 and 1,25(OH)2D3. Gross deletion of these segments in mice has severe consequences on skeletal health, and directl...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Publication date: Available online 16 October 2019Source: Chemico-Biological InteractionsAuthor(s): Yasmeen M. Attia, Dina M. El-Kersh, Reham A. Ammar, Aliaa Adel, Aya Khalil, Hoda Walid, Kirullos Eskander, Mohamed Hamdy, Nada Reda, Nour Elhoda Mohsen, Ghada M. Al-Toukhy, Mohamed Tarek Mansour, Mohamed M. ElmazarAbstractTreatment of breast cancer by paclitaxel (PAX) often encounters therapeutic failure most likely caused by innate/acquired resistance. Cancer stem cells (CSCs) and multidrug resistance complex (MDR-1 or P-glycoprotein) overexpression are main mechanisms implicated in chemoresistance. Increased aldehyde dehro...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Publication date: Available online 16 October 2019Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Jaini Flora Arokianathan, Koduvayur A Ramya, Asuma Janeena, Abhijit P. Deshpande, Niraikulam Ayyadurai, Ambrose Leemarose, Ganesh ShanmugamAbstractSupramolecular gel material built from low-molecular-weight (LMW) gelators finds potential applications in various fields, especially in drug delivery, cell encapsulation and delivery, and tissue engineering. The majority of the LMW gelators in these applications are based on functionalized peptides/amino acids consisting of proteinogenic amino acids which are proteolytical...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: Available online 15 October 2019Source: Microchemical JournalAuthor(s): Bruna Rosa da Silva Santos, Emmanuelle Ferreira Requião Silva, Lucas Almir Cavalcante Minho, Geovani Cardoso Brandão, Ana Maria Pinto dos Santos, Wagna Piler Carvalho dos Santos, Mariângela Vieira Lopes Silva, Walter Nei Lopes dos SantosABSTRACTCassava leaves (Manihot esculenta) are used to prepare “maniçoba”. Of indigenous origin, this dish is considered of high nutritional value for Brazilian cuisine. However, the leaves should be processed in order to eliminate the hydrocyanic acid that they c...
Source: Microchemical Journal - Category: Chemistry Source Type: research
Authors: Zasada M, Budzisz E Abstract Vitamin A is the first vitamin approved by the Food and Drug Administration as an anti-wrinkle agent that changes appearance of the skin surface and has anti-aging effects. Vitamin A is in a group of fat-soluble substances and belongs to the category of retinoids. Apart from retinol, that group includes structurally related substances with the biological properties of retinol. Since the biological activity of the substances differs, for the purpose of standardization, it is given in retinol equivalents. Vitamin A and its derivatives are among the most effective substances slowi...
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
Publication date: Available online 16 October 2019Source: American Journal of Kidney DiseasesAuthor(s): Youbao Li, J. David Spence, Xiaobin Wang, Yong Huo, Xiping Xu, Xianhui QinRationale &ObjectiveIn populations with folic acid fortification or supplementation, the main nutritional determinant of total homocysteine levels is vitamin B12 (B12) status. We aimed to evaluate the modifying effect of B12 levels on the association between folic acid treatment and chronic kidney disease (CKD) progression.Study DesignA post hoc analysis of an interventional trial.Setting &ParticipantsThis is a post hoc analysis of 1,374 hy...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Conclusions We found a contextual preventive effect of community-level sports group participation on developing cognitive impairment among older individuals. Furthermore, the benefit may favor sports group participants. Therefore, promoting sports groups in a community setting may be effective as a population-based strategy for the prevention of dementia.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: EPIDEMIOLOGY Source Type: research
CONCLUSION: AD causes impairment of EnA and ExA. Faster reactions by AD participants to the target on the left in VT+s and more accurate reactions to the target on the left in VT-s are in agreement with reports in the literature on the lateralization of visual-spatial attention (VSA) in the right hemisphere. In this study, also in agreement with previous reports, lateralization in AD was noted in favour of the stimuli on the left in ExA. PMID: 31613976 [PubMed - in process]
Source: Turkish Journal of Psychiatry - Category: Psychiatry Authors: Tags: Turk Psikiyatri Derg Source Type: research
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