Characteristics, management and outcomes of patients with acute liver failure admitted to Australasian intensive care units.
CONCLUSION: POD is the major cause of ALF in Australian and New Zealand liver transplant centres and is a unique and separate form of ALF. It has a much lower associated mortality and treatment with liver transplantation than non-POD ALF. Non-POD patients have a poor prognosis in the absence of transplantation. PMID: 31462206 [PubMed - in process]
Conn Med. 2018 Mar;82(3):133-137.ABSTRACTOpioid overdose and substance abuse treatment entry data suggest that injection drug use is increasing in nonurban locations. We sought to explore the prevalence and incidence of viral infections among people who inject drugs (PWID) residing in Fairfield and New Haven counties but outside of the six largest cities. A longitudinal cohort of PWID was assembled and incidence of HIV-1, hepatitis B virus, and hepatitis C virus infections was determined by annual antibody screening. Data on participants' socioeconomic situation and risk behaviors were collected. We identified 11 new hepat...
AbstractBackgroundThe hepatotoxicity of acetaminophen is recognised worldwide. Unfavourable prognoses relating to overdose include liver transplantation and/or death. Several hepatotoxicity risk factors (HRFs) should motivate the adjustment of acetaminophen daily intake (to
This report highlights tacrolimus as a potential trigger of posterior reversible encephalopathy syndrome and may inform clinical decisions regarding tacrolimus administration in liver transplant recipients with preexisting or newly developed posterior reversible encephalopathy syndrome. PMID: 30602365 [PubMed - as supplied by publisher]
BURLINGTON (CBS) – Doctors at Lahey Hospital told Matt Higgins a new liver was his only option for survival as chronic liver disease ravaged the Seabrook, New Hampshire man’s body. “My energy levels, I was down to nothing. I could barely walk a 100 yards without having to stop. I was jaundiced, completely yellow,” Higgins told WBZ-TV. When the call came that a liver transplant was available from a 24-year-old donor who had died from an opioid overdose, Higgins said, he did not hesitate. He immediately accepted it. “Being as sick as I was, of course I said yes. I’ll take anything that&rsq...