Long-term remission by brentuximab vedotin for non-mediastinal gray zone lymphoma refractory to autologous stem cell transplantation

Treatment for B-cell lymphoma unclassifiable with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma, especially in relapsed or refractory case, is not established. A 35-year-old Japanese woman with this type of lymphoma relapsed after ABVD chemotherapy received salvage chemotherapies. Even after hidh-dose chemotherapy followed by autologous stem cell transplantation, only partial response could be achieved. Consolidative involved-field radiation therapy did not induce complete response and four months later a new lesion appeared at the skin inside the irradiated field.

Source: Clinical Lymphoma, Myeloma and Leukemia - August 29, 2019 Category: Hematology Authors: Kazutoshi Ebisawa, Yosuke Masamoto, Junji Koya, Arika Shimura, Aya Shinozaki-Ushiku, Kazuhiro Toyama, Kumi Nakazaki, Mineo Kurokawa Tags: Case Report Source Type: research