Attitudes and perceived barriers toward arteriovenous fistula creation and use in hemodialysis patients in Jordan.

In conclusion, in this sample population from HD patients in Jordan, majority would recommend an AVF as mode of access. Perceived barriers include lack of timely referral for vascular surgical evaluation and poor understanding of disease. A systematic assessment of the process that precedes the creation of AVF, with focus on areas of reported barriers may allow for better utilization of AVF. PMID: 31464248 [PubMed - in process]
Source: Saudi Journal of Kidney Diseases and Transplantation - Category: Urology & Nephrology Authors: Tags: Saudi J Kidney Dis Transpl Source Type: research

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Authors: Campos-Borges HC, Sanz-González SM, Zanón-Moreno V, Millán Salvador JM, Pinazo-Duran MD PMID: 31629562 [PubMed - as supplied by publisher]
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
In this study, we assessed effects of LPZ on adipocyte differentiation and function by using 3T3-L1 preadipocytes and HFD-induced obesity mice as an in vitro and in vivo model, respectively.Main methodsOil red O staining and intracellular triacylglycerol content were used to determine lipid accumulation. Glucose uptake was performed to measure mature adipocyte function. Expression of adipocyte genes was determined by qRT-PCR and immunoblotting.Key findingsLPZ has dual effects on differentiation of 3T3-L1 cells. At low concentrations, LPZ enhanced adipocyte differentiation via induction of PPARγ and C/EBPα, two ...
Source: Life Sciences - Category: Biology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Publication date: Available online 20 October 2019Source: Microvascular ResearchAuthor(s): Wayne Smith, Konstantin E. Kotliar, Leandi Lammertyn, Nthai E. Ramoshaba, Walthard Vilser, Hugo W. Huisman, Aletta E. SchutteAbstractPurposeGlobally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis of systemic vascular diseases, but it is unclear whether retinal vessel calibers and acute retinal vessel functional responses differ between young healthy black and white adults.MethodsW...
Source: Microvascular Research - Category: Biochemistry Source Type: research
Publication date: Available online 21 October 2019Source: American Journal of Kidney DiseasesAuthor(s): Shannon A. Novosad, Priti R. Patel
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Publication date: Available online 21 October 2019Source: American Journal of Kidney DiseasesAuthor(s): Robert S. Brown
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Cavero et  al.1 recently reported the frequency and severity of hypertension in a cohort of 55 patients with atypical hemolytic uremic syndrome (aHUS). A major complication of hemolytic uremic syndrome is hypertensive crisis related to juxtaglomerular ischemia and renin angiotensin system activation. However , hypertensive crisis has been also described as a cause of thrombotic microangiopathy because of endothelial shear stress. Despite the persistent incidence of hypertensive crisis in developed and developing countries,2 the pathophysiological mechanisms and treatment of hypertensive crisis–associa ted hemoly...
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Letter to the Editor Source Type: research
We thank El Karoui and colleagues for their comments.1 We think that both studies, theirs and ours,2,3 show that severe hypertension is a characteristic feature of atypical hemolytic uremic syndrome (aHUS). Even their patients classified as aHUS not associated with hypertensive emergencies had a median blood pressure of 154/90 mm  Hg, which would include hypertension grades 1-2, according to the 2018 European Society of Cardiology/European Society of Hypertension guidelines.4 Unlike in their study, we found a favorable effect of eculizumab also in patients with severe and malignant hypertension.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Letter to the Editor Source Type: research
Changes in indices of mineral metabolism, bone protein expression, and bone turnover were assessed between pre – and post–renal transplant bone biopsies obtained 12 months apart. Circulating sclerostin and fibroblast growth factor 23 (FGF-23) levels decreased, and a low bone turnover state was highly prevalent on follow-up. In contrast, bone sclerostin expression increased, whereas FGF-23 bone expression was unchanged/decreased. These findings underscore the limitations of circulating biomarkers and the critical role of bone biopsy to understand osteocyte biology in chronic kidney disease–mineral bone disorder.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Commentary Source Type: research
This study was performed to evaluate the various etiologies of CKD among patients presenting to the Department of Nephrology, Guwahati Medical College, a tertiary referral center. A total of 5718 CKD patients were evaluated to identify the cause of CKD. The most common cause was found to be diabetes mellitus in 42.2%, followed by chronic glomerulonephritis in 21.4%, hypertension in 19.5%, obstructive uropathy in 6.9%, chronic interstitial nephritis in 3.6%, and autosomal dominant polycystic kidney disease in 1.5% of the patients. Nearly 2.7% of the patients had CKD of unknown etiology. Most of the common causes of CKD are ...
Source: Saudi Journal of Kidney Diseases and Transplantation - Category: Urology & Nephrology Authors: Tags: Saudi J Kidney Dis Transpl Source Type: research
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