T 2 mapping of the meniscus is a biomarker for early osteoarthritis

ConclusionIn vivo T2 mapping of the human meniscus correlates strongly with histological degeneration, suggesting that T2 mapping enables the detection and quantification of early compositional changes of the meniscus in knee OA.Key Points• Prospective histology-based study showed that in vivo T2mapping of the human meniscus correlates strongly with histological degeneration.• Meniscal T2mapping allows detection and quantifying of compositional changes, without need for contrast or special MRI hardware.• Meniscal T2mapping provides a biomarker for early OA, potentially allowing early treatment strategies and prevention of OA progression.

http://link.springer.com/10.1007/s00330-019-06091-1

Source: European Radiology - August 30, 2019 Category: Radiology Source Type: research