Immediate and delayed hypersensitivity after intra-arterial injection of iodinated contrast media: a prospective study in patients with coronary angiography

ConclusionThe incidence rate of immediate and delayed HSR in intra-arterially administered ICM was 3.6% and 15.1%, respectively. Previous exposure to intra-arterially administered contrast media was a significant risk factor for immediate HSR. Compared to ioversol, iodixanol was associated with relatively earlier and more frequent delayed HSR.Key Points• In this prospective study,the incidence of immediate and delayed hypersensitivity in intra-arterial injection of contrast media during coronary angiography was 3.6%and 15.1%,respectively.• Delayed hypersensitivity reactions were more common but less severe than immediate hypersensitivity reactions during coronary angiography.• Previous exposure to ICM viaintra-arterial route was a significant risk factor for immediate hypersensitivity to intra-arterial contrast medium.

Source: European Radiology - August 30, 2019 Category: Radiology Source Type: research