The Fault In Our Stars (TFIOS): An Insightful Depiction Of Teens Living With Serious Illness

I have to confess that even though I am a grown woman I seem to like many young adult–teenage books (I am still seventeen at heart). I am frequently asking my daughter and nieces about books they enjoyed when I’m looking for something to read. So far the books I have read include some teenage love stories happening in a futuristic dystopia in which the main characters are at risk of dying because of being in a arena fighting other children like in the hunger games; or being at risk of getting injured while performing difficult stunts like jumping from a train like in the divergent series. The Fault in Our Stars (TFIOS) by John Green is also about teens who fall in love and who are actually dying because they both have cancer. The book is narrated from the perspective of Hazel Lancaster a teenage girl with stage IV thyroid cancer metastatic to the lungs. Hazel uses a nasal cannula connected to an oxygen tank because her “lungs suck at being lungs”.   At the insistence of her parents she reluctantly attends a youth Cancer Support Group.  “Support Group featured a rotating cast of characters in various states of tumor-driven unwellness. Why did the cast rotate? A side effect of dying.”  However things drastically change when a gorgeous boy named Augustus “Gus” Waters suddenly appears at support group.  Augustus Waters is seventeen, he has osteosarcoma and had part of a leg amputated. Gus and Hazel...
Source: Pallimed: A Hospice and Palliative Medicine Blog - Category: Palliative Carer Workers Authors: Source Type: blogs

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I’m in the northeast, and it’s becoming a pain in the a** to eat anywhere. Everywhere is full, have to book a reservation way ahead to get anything. Many restaraunts have started to hold a credit card on file for reservation and charge fees for cancelation, seems to have made it better. Is this how it was pretty pandemic, I can’t remember? Is it this annoying other parts of the country? I will also add, I only sit down at a restaraunt with my spouse maybe once or twice a month.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
for Medicare advantage plan - EviCore require Orthopedic surgeon available at site for Vertebral Augmentation. Have any one come a cross that kind of situation ? What you do ?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
“My Alec, I am here to heal any of your pain that I can. I am not going anywhere,” Baldwin’s wife, Hilaria, professed online following the star’s ABC interview. #myalec #hilariabaldwin #rust
Source: Reuters: Health - Category: Consumer Health News Source Type: news
Propose of review To summarize the evidence that suggests that osteoarthritis (OA) is a mitochondrial disease. Recent findings Mitochondrial dysfunction together with mtDNA damage could contribute to cartilage degradation via several processes such as: (1) increased apoptosis; (2) decreased autophagy; (3) enhanced inflammatory response; (4) telomere shortening and increased senescence chondrocytes; (5) decreased mitochondrial biogenesis and mitophagy; (6) increased cartilage catabolism; (7) increased mitochondrial fusion leading to further reactive oxygen species production; and (8) impaired metabolic flexibilit...
Source: Current Opinion in Rheumatology - Category: Rheumatology Tags: OSTEOARTHRITIS: Edited by Mukundan Attur Source Type: research
Purpose of review To review the recent literature on bone in osteoarthritis (OA), with a focus on imaging and intervention studies Recent findings Most studies focused on knee OA; hip and hand studies were uncommon. Bone shape studies demonstrated that shape changes precede radiographic OA, predict joint replacement, and have demonstrated high responsiveness. Novel quantitative 3D imaging markers (B-score) have better characterized OA severity, including preradiographic OA status. The addition of computerized tomography-derived 3D metrics has improved the prediction of hip joint replacement when compared to radi...
Source: Current Opinion in Rheumatology - Category: Rheumatology Tags: OSTEOARTHRITIS: Edited by Mukundan Attur Source Type: research
Below are moments from my intern year of general surgery residency. They represent moments that occurred over three years ago, which I took home to my journal to process and work through. Back then, the moments left me speechless. And today, re-visiting them, the moments clearly demonstrate the fragility of the human spirit. A silentlyRead more …The pain of doctoring and a call for change originally appeared
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Physician Surgery Source Type: blogs
Stomach cancer is one of the least common cancers in the United Kingdom. The estimated lifetime risk of being diagnosed with stomach cancer is at least one in seventy-six for men born after 1960, according to Cancer Research UK. Nevertheless, it is helpful to know the symptoms just in case you start to feel unwell.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: These results suggested that activation of α2A -ARs by DEX suppressed P2X3 receptor-mediated electrophysiological and behavioral activity via a Gi/o proteins and cAMP signaling pathway, which was a novel potential mechanism underlying analgesia of peripheral α2A -AR agonists.PMID:34862748 | DOI:10.1111/cns.13774
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Source Type: research
Reprod Biol Endocrinol. 2021 Dec 3;19(1):178. doi: 10.1186/s12958-021-00860-8.ABSTRACTOvarian cancer is the fifth leading cause of cancer-related mortality in women worldwide. Despite the development of technologies over decades to improve the diagnosis and treatment of patients with ovarian cancer, the survival rate remains dismal, mainly because most patients are diagnosed at a late stage. Traditional treatment methods and biomarkers such as cancer antigen-125 as a cancer screening tool lack specificity and cannot offer personalized combinatorial therapy schemes. Circulating tumor DNA (ctDNA) is a promising biomarker for...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Source Type: research
In this study, we explored whether LA has an anti-aging effect in adipose-derived stem cells (ADSCs). We performed β-galactosidase staining and measured reactive oxygen species, relative telomere lengths, and P16ink4a mRNA expression. Osteogenesis was assessed by Alizarin Red staining and adipogenesis by was assessed Oil Red O staining. Protein levels of related markers runt-related transcription factor 2 and lipoprotein lipase were also examined. RNA sequencing and measurement of glycolysis activities showed that LA significantly activated glycolysis in ADSCs. Together, our data strongly suggest that the LA have an a...
Source: Aging - Category: Biomedical Science Authors: Source Type: research
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