Selective Inhibitors of Nuclear Export in the treatment of hematological malignancies

We reported results of preclinical studies and clinical trials and discussed the mechanism of action of SINEs and their effects in multiple myeloma, non-Hodgkin lymphomas, lymphoblastic leukaemia, acute and chronic myeloid leukaemia.In the next future the numerous experimental studies currently underway will allow us to define the role of the SINEs and the possibility of introducing these substances into daily clinical practice.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research