Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of non-alcoholic steatohepatitis.

CONCLUSION: This study provides a novel 3-week dietary model of mice that rapidly develop NASH features, and this model will be suitable for evaluating the therapeutic efficacy of compounds in preclinical drug development for NASH.
PMID: 31460789 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - August 27, 2019 Category: Physiology Authors: Duparc T, Briand F, Trenteseaux C, Mérian J, Combes G, Najib S, Sulpice T, Martinez LO Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research