Renovascular disease induces mitochondrial damage in swine scattered tubular cells.

Conclusions: RVD in swine is associated with a higher prevalence of STCs, but induces structural and functional alterations in STC mitochondria, which impair their reparative potency. These observations suggest a key role for mitochondria in the renal reparative capacity of STCs.
PMID: 31461348 [PubMed - as supplied by publisher]

Source: Am J Physiol Renal P... - August 27, 2019 Category: Urology & Nephrology Authors: Aghajani Nargesi A, Zhu XY, Conley SM, Woollard JR, Saadiq IM, Lerman LO, Eirin A Tags: Am J Physiol Renal Physiol Source Type: research