Evolution of treatment strategies for oligometastatic NSCLC patients - A systematic review of the literature

Metastatic NSCLC has long been thought of as incurable and treatment consisted mainly of palliative chemotherapy (CHT). Local treatments, such as surgery or radiotherapy, with palliative, non-ablative doses were restricted to symptom control. The concept of oligometastatic disease (OMD) is currently challenging this dogma by defining an intermediate stage of metastatic disease with a more favorable disease biology and dynamic. OMD is characterized by a limited number of metastatic lesions and a low overall metastatic burden that opens a therapeutic window for radical treatment to all cancer sites, the locoregional primary tumor and oligometastases.
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Systematic or Meta-analysis Studies Source Type: research