Severe Obsessive-Compulsive Disorder Secondary to Neurodegeneration With Brain Iron Accumulation: Complete Remission After Subthalamic Nuclei Deep Brain Stimulation

Neurodegeneration with brain iron accumulation (NBIA) is defined as an accumulation of iron in the basal ganglia associated with neurologic and psychiatric symptoms (1). Its estimated prevalence is 1:1,000,000 (2). Cardinal symptoms include dystonia; spasticity and/or Parkinsonian syndrome, often associated with cognitive decline (3,4); and psychiatric disorders such as obsessive-compulsive disorder (OCD) (3,5,6), depression (7), or psychosis (8).
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Correspondence Source Type: research