Transient Epileptic Amnesia: A Treatable Cause of Spells Associated With Persistent Cognitive Symptoms

Conclusions: TEA is a treatable cause of amnestic spells in older adults. This syndrome is frequently associated with persistent interictal cognitive/behavioral symptoms and thus can be mistaken for common mimics. In the appropriate clinical context, our findings support the use of early prolonged EEG with emphasis on sleep monitoring as a key diagnostic tool. FDG-PET may also complement MRI in distinguishing TEA from neurodegenerative disease when suspected.
Source: Frontiers in Neurology - Category: Neurology Source Type: research

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Publication date: November 2018Source: Epilepsy &Behavior, Volume 88Author(s): Jacopo Lanzone, Lorenzo Ricci, Giovanni Assenza, Martina Ulivi, Vincenzo Di Lazzaro, Mario TombiniAbstractObjectiveTransient epileptic amnesia (TEA) is an underestimated condition in emergency clinical setting, where most of transient amnesic episodes tend to be classified as transient global amnesia (TGA). We designed this study to evaluate the actual frequency of TEA in a real-life scenario and to highlight the features that can help clinicians distinguishing it from TGA.MethodsWe retrospectively collected clinical data of 83 patients who ...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Abstract OBJECTIVE: Transient epileptic amnesia (TEA) is an underestimated condition in emergency clinical setting, where most of transient amnesic episodes tend to be classified as transient global amnesia (TGA). We designed this study to evaluate the actual frequency of TEA in a real-life scenario and to highlight the features that can help clinicians distinguishing it from TGA. METHODS: We retrospectively collected clinical data of 83 patients who accessed our emergency ward for an abrupt onset of amnesic disorder, initially interpreted as TGA. All patients underwent neurological evaluation, magnetic reson...
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
Authors: Klobucnikova K, Siarnik P, Muchova I, Štofko J, Kollar B Abstract The aim of this study is to remind the possibility of co-occurrence of epilepsy and narcolepsy. In the first case report, narcolepsy type 1 was diagnosed in 29-year-old female. After one year of the treatment with modafinil a new episodes of automatic behavior appeared. Patient was reevaluated and the diagnosis of focal epilepsy with partial complex seizures was established. Patient was treated with modafinil and lamotrigine and became seizure-free. In the second case report a 21-year-old female was referred with a typical histor...
Source: Neuroendocrinology Letters - Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research
Discussion Sleep disorders are common in all ages particularly sleep deprivation in our increasingly busy world. A review of health problems caused by inadequate sleep can be found here. Sleep problems are more common in patients with attention deficit hyperactivity disorder, epilepsy, headache and visual impairments. Sleep problems can cause cognitive and behavioral impairments including emotional regulation problems, increased seizures or headaches, and impaired attention and has been known to prolong recovery from various acquired brain injuries. Somnambulism or sleepwalking is a parasomnia (which include confusional a...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Conclusions: In patients ≥60 years of age, the correct identification of characteristic CNS syndromes (FBDS, anti-IgLON5 syndrome, AE) should prompt antibody testing even without evidence of inflammation in MRI and CSF studies. Up to 15% of the patients developed rapidly progressive cognitive deterioration, which further complicated the differential diagnosis with a neurodegenerative disorder.
Source: Neurology - Category: Neurology Authors: Tags: Autoimmune diseases, Encephalitis, All Clinical Neurology, All Epilepsy/Seizures ARTICLE Source Type: research
While I was taking care of my mom, Dotty, I often worried about seizures. Silent Seizures.My mother often suffered from severe headaches particularly in the morning. This was an ongoing problem that would come and go. The research below indicates that the silent seizures occurred while patients were sleeping..I actually received training on what to look for, and the signs and symptoms of seizures.6 reasons why you might have to put someone with dementia in a memory care facility or nursing homeBy Bob DeMarcohttp://www.alzheimersreadingroom.comSubscribe to the Alzheimer's Reading RoomEmail:I clearly remember our doctor...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer's care caring for dementia patients at home dementia care dementia confusion family caregiving home care memory care facility nursing home seizures in alzheimer patients Source Type: blogs
Abstract Transient epileptic amnesia (TEA) is a sub-type of mesial temporal lobe epilepsy, with amnesic seizures. TEA is characterized by recurrent episodes of amnesia. Diagnostic criteria are available for TEA, and these memory disturbances should not be misdiagnosed with transient global amnesia. The neuropsychological evaluation is normal, however, autobiographical memory impairment is present in 70% of the cases and accelerated long term forgetting in 44%. When a patient complains of memory disturbances, especially autobiographical memory, TEA must be considered especially if there was an amnesic episode and s...
Source: Presse Medicale - Category: Journals (General) Authors: Tags: Presse Med Source Type: research
A 38-year-old, right-handed woman presented to the epilepsy clinic for evaluation of recurrent spells. These spells are characterized by an aura of a "rushing" cephalic sensation and a sense of "spaciness" or "dizziness" followed by loss of awareness with subsequent amnesia for the event. During these events, the patient is observed by family to sit down and slump forward or fall, followed by hyperventilation and occasionally staring, for up to 3 minutes. There is no head turn, eye deviation, or abnormal body movements. Postictally, she reports generalized weakness without focality and confusi...
Source: Neurology - Category: Neurology Authors: Tags: Other cerebrovascular disease/ Stroke, Clinical neurology examination, Syncope, Epilepsy monitoring, Nonepileptic seizures RESIDENT AND FELLOW SECTION Source Type: research
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and th...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research
Encephalitis associated with antibodies against leucine-rich glioma-inactivated 1 (LGI1) protein is increasingly recognized as an auto-immune disorder associated with characteristic tonic-dystonic seizures. The cortical or subcortical origin of these motor events is not clear. Some patients also present with different epileptic seizures and with cognitive impairment. The frequency of these features and their timing during the natural history of this encephalitis have not been fully described. We therefore reviewed data from 34 patients harbouring antibodies against LGI1 protein (21–81 years, median age 64) referred t...
Source: Brain - Category: Neurology Authors: Tags: Epilepsy and Sleep Original Articles Source Type: research
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