Variability in gelatinase expression in the walls of vessels used as aortocoronary conduits may impact long-term graft patency.

CONCLUSIONS: Imbalance in the metalloproteinase-to-inhibitor tissue expression in the vessel wall might predispose to graft failure. A stronger expression of TIMPs than MMPs in the arterial grafts might explain favourable long-term outcomes.
PMID: 30676640 [PubMed - indexed for MEDLINE]

Source: Kardiologia Polska - August 28, 2019 Category: Cardiology Authors: Perek B, Kowalska K, Nowicki M, Kempisty B, Puślecki M, Jankowski M, Jemielity M, Malińska A Tags: Kardiol Pol Source Type: research