Guidelines May Speed Obesity Hypoventilation Syndrome Diagnosis Guidelines May Speed Obesity Hypoventilation Syndrome Diagnosis

With the condition considered"vastly undiagnosed," recommendations include simplified screening, optimal treatment options.Medscape Medical News
Source: Medscape Emergency Medicine Headlines - Category: Emergency Medicine Tags: Diabetes & Endocrinology News Source Type: news

Related Links:

Around 13million people over the age of 16 were considered obese in 2017 - up from the 6.9million recorded back in 1997, according to the analysis by the charity Diabetes UK.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Contributors : Martin G Scherm ; Carolin Daniel ; Benedikt KirchnerSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensIn type 1 diabetes (T1D), the appearance of multiple islet autoantibodies indicates the onset of islet autoimmunity, often many years before clinical symptoms arise. However, the underlying molecular mechanisms in T cells that can promote aberrant activation thereby triggering autoimmune progression remain poorly understood. Here, we show that during early stages of islet autoimmunity a miRNA142-3p/Tet2 signaling axis in murine and human CD4+T cells interferes with th...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by high throughput sequencing Homo sapiens Source Type: research
Contributors : Martin G Scherm ; Carolin Daniel ; Jonathan SchugSeries Type : OtherOrganism : Homo sapiensIn type 1 diabetes (T1D), the appearance of multiple islet autoantibodies indicates the onset of islet autoimmunity, often many years before clinical symptoms arise. However, the underlying molecular mechanisms in T cells that can promote aberrant activation thereby triggering autoimmune progression remain poorly understood. Here, we show that during early stages of islet autoimmunity a miRNA142-3p/Tet2 signaling axis in murine and human CD4+T cells interferes with the efficient induction of regulatory T (Treg) cells a...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Other Homo sapiens Source Type: research
Publication date: Available online 13 November 2019Source: Clinica Chimica ActaAuthor(s): Xin Zeng, Yuan-jie Xie, Ya-ting Liu, Shuang-lian Long, Zhong-cheng MoAbstractPolycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic abnormalities, including insulin resistance, excessive weight or obesity, type II diabetes, dyslipidemia and an increased risk of cardiovascular disease. The most significant clinical manifestation of PCOS is hyperandrogenism. Excess androgen profoundly affects granulosa cell function and...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
The metabolic syndrome (MetS) comprises abdominal obesity, preclinical or full diabetes type 2, arterial hypertension, and dyslipidemia and affects a significant proportion of the general population with a remarkably higher prevalence in patients suffering from psychiatric disorders. However, studies exploring the pathogenetic link between MetS and psychiatric diseases are rare. Here, we aim to narrow this gap in knowledge by providing a narrative review on this topic that focuses on two psychiatric diseases, namely on schizophrenia and posttraumatic stress disorder (PTSD) since we assume them to be associated with two dif...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Background: Insulin resistance, the primary mechanism of metabolic syndrome, promotes gastric carcinogenesis. Metabolic syndrome is associated with sarcopenia. We aimed to investigate the association between sarcopenia and gastric carcinogenesis, including precancerous conditions such as atrophic gastritis (AG), intestinal metaplasia (IM), and dysplasia.Methods: The study included adult patients who underwent gastroduodenoscopy at a checkup center. AG and IM were evaluated using endoscopy. Based on muscle mass, sarcopenia was defined as a skeletal muscle index
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
New strategy to reduce diabetes cases and improve treatment Related items fromOnMedica Public support for calorie labelling in restaurants Warning issued on high sugar content in snacks Weight loss targets exceeded on NHS type 2 diabetes prevention programme Diabetes and obesity higher among LGBQ teens Obesity should be recognised as a disease, say experts
Source: OnMedica Latest News - Category: UK Health Source Type: news
Obesity, insulin resistance, dyslipidemia, and hypertension are fundamental clinical manifestations of the metabolic syndrome. Studies over the last few decades have implicated chronic inflammation and microvascular remodeling in the development of obesity and insulin resistance. Newer observations, however, suggest that dysregulation of the lymphatic system underlies the development of the metabolic syndrome. This review summarizes recent advances in the field, discussing how lymphatic abnormality promotes obesity and insulin resistance, and, conversely, how the metabolic syndrome impairs lymphatic function. We also discu...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Publication date: Available online 13 November 2019Source: PeptidesAuthor(s): Nigel Irwin, Victor A. Gault, Finbarr P.M. O’Harte, Peter R. FlattAbstractGastric inhibitory polypeptide (GIP) is a 42 amino acid hormone secreted from intestinal K-cells in response to nutrient ingestion. Despite a recognised physiological role for GIP as an insulin secretagogue to control postprandial blood glucose levels, growing evidence reveals important actions of GIP on adipocytes and promotion of fat deposition in tissues. As such, blockade of GIP receptor (GIPR) action has been proposed as a means to counter insulin resistance, and...
Source: Peptides - Category: Biochemistry Source Type: research
More News: Diabetes | Eating Disorders & Weight Management | Emergency Medicine | Endocrinology | Obesity