HRS 40th anniversary viewpoints: Carpe diem

They tell me that when I was 7 years old, when asked what I wanted to be when I grew up, I unhesitatingly answered, “a cardiologist.” Except for 2 weeks in college I never ever wavered. My father, who escaped from Russia, was a first-class cardiologist and clinician with superb ears, hands, and brain, who could diagnose a pancreatic mass by palpation. I used to go with him to his hospital in New York City jus t to be in the medical environment. He communicated with the greats in the field if he had questions or comments and wrote many original papers, mainly having to do with electrocardiography (which I typed for him when I learned how and mounted the figures—electrocardiograms [ECGs]—sometimes cut too small).
Source: Heart Rhythm - Category: Cardiology Authors: Tags: Viewpoint Source Type: research

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In this study, 102 sets of single-lead ECG data from 19 healthy subjects were analyzed. The signal-to-noise ratio of ECG, as well as the mean and coefficient of variation of QRS amplitude, was derived among different channels to determine the optimal electrode locations. The results showed that a single-lead electrode pair should be placed on the left chest above the electrode location of standard precordial leads V1 to V4. Additionally, the best orientation was the principal diagonal as the direction of the heart’s electrical axis.
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
ir Krajca Simultaneous recordings of electroencephalogram (EEG) and functional magnetic resonance imaging (fMRI) are at the forefront of technologies of interest to physicians and scientists because they combine the benefits of both modalities—better time resolution (hdEEG) and space resolution (fMRI). However, EEG measurements in the scanner contain an electromagnetic field that is induced in leads as a result of gradient switching slight head movements and vibrations, and it is corrupted by changes in the measured potential because of the Hall phenomenon. The aim of this study is to design and test a methodolog...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
This report demonstrates the variable cardiac rhythm in two species of subterranean mole, the large Japanese mole (Mogera wogura) and the lesser Japanese mole (Mogera imaizumii). The phenomenon was revealed using X-ray videos ofM. wogura and investigated in detail using electrocardiogram (ECG) traces recorded with implanted electrodes in this species andM. imaizumii. Cessation of heartbeat and extendedR–R intervals were observed in the ECGs from both species during short bouts of rest in wakeful specimens of both species under normoxic conditions at room temperature. The mean durations ofR–R intervals were 288....
Source: Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology - Category: Physiology Source Type: research
ConclusionThe likelihood of AF detection by an ILR in the first month post-CS is low. Thus, the diagnostic yield of 30  days of AECG monitoring is likely to be limited. These data suggest a rationale for proceeding directly to ILR implantation prior to hospital discharge in CS patients, as many have AF detected during longer follow-up.
Source: Journal of Interventional Cardiac Electrophysiology - Category: Cardiology Source Type: research
Publication date: Available online 12 October 2019Source: Life SciencesAuthor(s): Liang Qiao, Yan Kong, Yingshen Shi, Aijun Sun, Ruijuan Ji, Chao Huang, Yuquan Li, Xiangqun YangAbstractAimsThe aims of the study are to investigate whether the combination of adipose-derived stem cells (ADSCs) with decellularized extracellular matrix (dECM) of myocardium can exert synergistic therapeutic effects on acute MI and the underlying mechanism.Main methodsMyocardial dECM from fresh porcine myocardium was prepared in an injectable gel, ADSCs were seeded into the myocardial dECM gels, and then the mixture was injected into the myocardi...
Source: Life Sciences - Category: Biology Source Type: research
Sensors, Vol. 19, Pages 4426: Textile-Friendly Interconnection between Wearable Measurement Instrumentation and Sensorized Garments—Initial Performance Evaluation for Electrocardiogram Recordings Sensors doi: 10.3390/s19204426 Authors: Fernando Seoane Azadeh Soroudi Ke Lu David Nilsson Marie Nilsson Farhad Abtahi Mikael Skrifvars The interconnection between hard electronics and soft textiles remains a noteworthy challenge in regard to the mass production of textile–electronic integrated products such as sensorized garments. The current solutions for this challenge usually have problems w...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
AbstractA 34-year-old man, who was previously fit and healthy, died suddenly on exercise. A post-mortem exam performed by forensic pathologists and a toxicological screening were normal; therefore, the cause of death was suspected to be sudden arrhythmic death syndrome, prompting the need for a molecular autopsy. Screening for genetic variations underlying arrhythmogenic genes by next-generation sequencing highlighted a heterozygoussingle-nucleotide variant in the exon n. 94 of theryanodine receptor type 2 gene. This gene, encoding the cardiac ryanodine receptor, is one of the main genetic variants of catecholaminergic pol...
Source: International Journal of Legal Medicine - Category: Medical Law Source Type: research
AbstractPurposeCardiovagal baroreflex sensitivity (cvBRS) reflects the efficiency of modulating heart rate in response to changes in systolic blood pressure. International guidelines recommend that older adults achieve at least 150  min of moderate–vigorous physical activity per week. We tested the hypothesis that older adults who achieve these guidelines will exhibit greater cardiovagal baroreflex sensitivity versus those who do not.MethodsA cross-sectional comparison of older adults who did (active, 66  ± 5 years, 251 ± 79 min/week;n = 19) and w...
Source: Clinical Autonomic Research - Category: Research Source Type: research
iRhythm and Verily announced a partnership last month to “co-develop solutions intended to provide early warning, diagnosis and management for patients, particularly for those with silent or undiagnosed AF.” We spoke with iRhythm CEO Kevi...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Diagnostics Exclusive irhythm verily Source Type: blogs
ConclusionThe ECG signal representing the electrical activity of the heart at different time intervals involves some important information. The signal is considered as one of the common tools used by physicians to diagnose various cardiovascular diseases, but unfortunately the proper diagnosis of disease in many cases is accompanied by an error due to limited time accuracy and hiding some important information related to this signal from the physicians' vision leading to the risks of irreparable harm for patients. Based on the results, designing the proposed alarm system can help physicians with higher speed and accuracy i...
Source: IRBM - Category: Biomedical Engineering Source Type: research
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