Endovascular Repair of Ascending Aortic Disease in High-Risk Patients Yields Favorable Outcome

ConclusionsAscending aortic stent placement for ascending aortic disease is feasible and is associated with favorable aortic remodeling. Despite persistent perfusion to the false lumen in a subset of patients, there is minimal aortic dilation at short-term follow-up with excellent survival.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

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Endovascular treatment options for thoracic aortic pathologies are increasing with the availability of new technologies and techniques. Although open surgery has traditionally been the primary treatment strategy for the ascending aorta and aortic arch, endovascular therapy, including fenestrated and branched stent grafts, has become an alternative treatment option. This applies, in particular, to patients not suitable for open surgery, a number expected to increase with the ageing population.1 During thoracic endovascular aortic aneurysm repair (TEVAR) stroke occurs in up to 20% for complex procedures.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Editorial Source Type: research
Authors: Paraskevas KI, Eckstein HH, Mikhailidis DP, Veith FJ, Spence JD Abstract Stroke is a leading cause of death and disability worldwide. Approximately 15% of all first-ever strokes occur due to atheroembolism from a previously undetected/untreated asymptomatic carotid stenosis (ACS). Despite that, international guidelines do not recommend screening for ACS. The rationale for not recommending screening include: a) the harm associated with screening, b) the questionable clinical benefit associated with surgery, c) the lack of proven reduction in the risk of stroke, d) the large number of false positive/false ne...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
by Sylvia T. Nurnberg, Marie A. Guerraty, Robert C. Wirka, H. Shanker Rao, Milos Pjanic, Scott Norton, Felipe Serrano, Ljubica Perisic, Susannah Elwyn, John Pluta, Wei Zhao, Stephanie Testa, YoSon Park, Trieu Nguyen, Yi-An Ko, Ting Wang, Ulf Hedin, Sanjay Sinha, Yoseph Barash, Christopher D. Brown, Thomas Quertermous, Daniel J. Rader Genome-wide association studies have identified multiple novel genomic loci associated with vascular diseases. Many of these loci are common non-coding variants that affect the expression of disease-relevant genes within coronary vascular cells. To identify such genes on a genome-wide level, ...
Source: PLoS Genetics - Category: Genetics & Stem Cells Authors: Source Type: research
Authors: Cífková R, Krajčoviechová A Abstract Epidemiologic studies consistently report a U-shaped curve relationship between the amount of alcohol consumption and cardiovascular disease, with consumption of ≥ three alcoholic drinks being associated with an increased risk. However, the cardioprotective effect of light and moderate alcohol consumption has been recently questioned. In the absence of a randomized trial confirming the cardioprotective effect of light or moderate alcohol consumption, an alternative method to prove the causality is Mendelian randomization using a genetic variant ...
Source: Central European Journal of Public Health - Category: International Medicine & Public Health Tags: Cent Eur J Public Health Source Type: research
This study aimed to describe experience of a specific protocol for endovascular aortic repair in patients with MFS. METHODS: All MFS patients treated by aortic endovascular repair between February 2015 and August 2018 were included prospectively. The following rules were applied: (i) excluding stent grafts with bare stents and barbs, (ii) proximal landing in a pre-existing graft, or (iii) minimising proximal oversizing when landing in the proximal native aorta (
Source: PubMed: Eur J Vasc Endovasc ... - Category: Surgery Authors: Tags: Eur J Vasc Endovasc Surg Source Type: research
This study investigated the association of bile acid excretion (BAE) with stroke incidence and mortality.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
CONCLUSION: Valve replacement in patients with hugely dilated left ventricle are safe operations with satisfactory outcomes even if combined with other procedures, especially with proper preoperative preparation, intraoperative preservation of posterior mitral leaflet, and meticulous postoperative follow up in the surgical ICU. PMID: 31895029 [PubMed - in process]
Source: The Heart Surgery Forum - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Heart Surg Forum Source Type: research
Purpose of review To summarize recent data on the role of dyslipidaemia and the benefit from managing this in people with disease of the abdominal aorta and its peripheral branches (peripheral artery disease, PAD). Recent findings Findings from the Further Cardiovascular Outcomes Research with Proprotein convertase subtilisin/kexin type 9 (PCSK9) Inhibition in Subjects with Elevated Risk (FOURIER) trial demonstrate the benefit of intensely lowering low-density lipoprotein-cholesterol (LDL-c) in people with PAD to substantially reduce the incidence of major cardiovascular events (MACE; myocardial infarction, stroke or ...
Source: Current Opinion in Lipidology - Category: Lipidology Tags: THERAPY AND CLINICAL TRIALS: Edited by Erik S.G. Stroes and Gerald F. Watts Source Type: research
ConclusionThis study shows high technical success and early lower limb reperfusion using PLS with trans-brachial access. The risk of stroke, especially in female patients, should be carefully assessed by review of preoperative arch imaging.
Source: CardioVascular and Interventional Radiology - Category: Radiology Source Type: research
ConclusionThe learning curve with the FET procedure had a significant impact on hospital mortality and midterm survival over the follow ‐up period, albeit did not influence the freedom from reintervention on the downstream aorta.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
More News: Abdominal Aneurysm Repair | Aortic Aneurysm | Cardiovascular & Thoracic Surgery | CT Scan | Endovascular Coiling | Endovascular Repair (EVAR) | Gastroschisis Repair | Heart Valve Surgery | Pathology | Perfusion | PET Scan | Stroke