Comparison of the ED50 and ED95 of Intrathecal Bupivacaine in Parturients Undergoing Cesarean Delivery With or Without Prophylactic Phenylephrine Infusion: A Prospective, Double-Blind Study

(Reg Anesth Pain Med. 2018;43(8):885–889) Spinal-induced hypotension is a common problem resulting from the sympathectomy associated with the administration of intrathecal local anesthetic for cesarean delivery, and is associated with nausea, vomiting, loss of consciousness, impaired fetal oxygenation, and fetal acidosis. Prophylactic phenylephrine infusion is often used to decrease the risk of spinal-induced hypotension; however, its use has been associated with decreased rostral spread of intrathecal local anesthetic in pregnancy. The purpose of this study was to determine the median effective dose (ED50) and 95% effective dose (ED95) of spinal hyperbaric bupivacaine for cesarean delivery with and without a phenylephrine infusion.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Anesthesia and Analgesia: Regional Anesthesia Source Type: research

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Study Design. Retrospective study. Objective. To investigate the association between gestational weight gain (GWG) during pregnancy and persistent low back and pelvic pain (LBPP) after delivery. Summary of Background Data. Persistent LBPP after delivery is a risk factor for developing depression and chronic pain as well as incurring sick leave. Women experience weight gain during pregnancy. Excessive weight gain places a greater burden on the musculoskeletal system. However, little is known about how GWG is associated with LBPP after delivery. Methods. After Ethics Committee approval, we analyzed 330 women at 4 ...
Source: Spine - Category: Orthopaedics Tags: EPIDEMIOLOGY Source Type: research
Most anyone who has struggled with secondary infertility knows that it is an incredibly lonely experience. You may be blessed with one or two children — possibly more — but struggling to expand or complete your family. Surrounded by families with young children, you find yourself alone and in pain. If you are a veteran of primary infertility, you may remember strategies you developed for shielding yourself from the pregnancies of others. Not so this second time around: pregnant women and moms with babies and toddlers surround you at preschool. If you had your first child with ease and are new to infertility, yo...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Infertility Men's Health Parenting Relationships Women's Health Source Type: blogs
ConclusionsThe prognosis following PGP in pregnancy is good and the majority of women recovered substantially from severe and moderate pregnancy-related PGP within 6  weeks after delivery. For many women, a subjective substantial recovery occurred within 2 weeks after delivery. Predictors for a poor recovery were multiparity, PGP the year before pregnancy and a high pain intensity during pregnancy.Graphic abstractThese slides can be retrieved under Electronic Supplementary Material.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
ConclusionBoth TA and AS have no significant adverse effects on pregnancy if diagnosed and timely treated properly. When they occur concomitantly, more attention and care is needed to prevent complications.
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
Journal of Clinical Sleep Medicine,Volume 16, Issue 1, Page 155-156, January 2020.
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Authors: Source Type: research
CONCLUSION: Herpes simplex virus hepatitis causes significant morbidity, and pregnant women are susceptible to severe infections. Pregnant or peripartum women with acute febrile hepatitis require prompt evaluation for HSV with serum PCR screening. PMID: 31923059 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
Conclusion: The stronger evidence about PLPB and PPs rehabilitative effect and safety will be provided for clinicians and policymakers. Systematic review registration: PROSPERO CRD 42017075099.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Several interactive pelvic axes occur during activities of weight-bearing and ambulation. Flexion and extension of the symmetrical innominates occur on the sacral x-axis with weight-bearing. Normal asymmetric innominate rotation occurs on the innominate axis at the pubic symphysis during weight-bearing with normal ambulation. Oblique sacral movement occurs on an oblique sacral axis concurrent with asymmetric innominate movement. Acute and chronic low back pain is commonly caused by a bilateral symmetrical or oblique anterior innominate rotation on the sacrum on an acetabular axis, usually while lifting, bending, lowering, ...
Source: Topics in Geriatric Rehabilitation - Category: Geriatrics Tags: Thieves' Market Source Type: research
BOSTON (CBS) — Imagine giving birth to a premature baby and then being told you have a brain tumor. That’s what happened to a woman from Holden. But thanks to a new approach at Brigham and Women’s Hospital, this new mom was able to have brain surgery and quickly return to her newborn son. At 27 weeks pregnant, Bethany Shea was diagnosed with preeclampsia and had an emergency C-section. Then she went blind. “It was a pregnancy complication due to my high blood pressure,” Bethany explained. Bethany regained her vision, but worried she had had a stroke, doctors ordered an MRI. But instead of a st...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Seen On WBZ-TV Syndicated CBSN Boston Syndicated Local Brigham and Women's Hospital Dr. Mallika Marshall Source Type: news
Wrapping up this year and looking back on the particularly interesting developments in medical technology, we at Medgadget are impressed and very excited about the future. We’re lucky to cover one of the most innovative fields of research and o...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Source Type: blogs
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