Onset of frontal fibrosing alopecia during inhibition of Th1/17 Pathways with ustekinumab.

We present a 62-year-old woman who developed persistent FFA while on ustekinumab for treatment of preexisting psoriasis. This case presents evidence against Th1 and Th17 pathways as essential to pathogenesis in FFA. This case also suggests that IL-12 and IL-23 inhibition is ineffective for this form of scarring alopecia. PMID: 31450280 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31450280?dopt=Abstract

Source: Dermatol Online J - July 14, 2019 Category: Dermatology Authors: King AD, Lam L, Goh C Tags: Dermatol Online J Source Type: research

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