Clinical profile, drug resistance pattern and treatment outcomes of abdominal tuberculosis patients in western india

CONCLUSION: Abdominal tuberculosis with wide spectrum of presentation, can still be managed with early diagnosis and treatment even in patients with sub acute intestinal obstruction. Weight gain or resolving symptoms were considered early markers of treatment response. Patients with stricture can become asymptomatic with medical treatment alone.RESUMO CONTEXTO: A tuberculose abdominal é um problema crescente no mundo em desenvolvimento. OBJETIVO: O objetivo do estudo foi descrever as apresentações clínicas, o padrão de resistência a fármacos e os desfechos de tratamento da tuberculose abdominal na Índia ocidental. MÉTODOS: Foram incluídos todos os casos de tuberculos e abdominal de maio de 2014 a abril de 2017, diagnosticados com base no perfil clínico e nos resultados morfológicos brutos na endoscopia, imagem latente, seguido pela histologia e/ou pela cultura de GeneXpert e de MGIT. Todos os pacientes receberam a terapia antitubercular da droga (AKT) de acord o com o protocolo nacional. Os pacientes foram acompanhados de diagnósticos até a conclusão do tratamento e vários parâmetros foram estudados. RESULTADOS: Dos 176 pacientes, 48% eram do sexo masculino. A dor abdominal foi a queixa mais comum em 83,5%. Na colonoscopia, o íleo terminal e a vá lvula íleo-cecal foram os segmentos mais comumente envolvidos. O trato gastrointestinal superio...
Source: Arquivos de Gastroenterologia - Category: Gastroenterology Source Type: research

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Some things you may need to know.  Nothing last week as I was " on holiday " , so two weeks'worth this time.COVID-19A systematic scoping review of COVID-19 during pregnancy and childbirth (International Journal of Obstetrics and Gynecology)ResearchProgression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis (BMJ)**Leicester authors**Comparative impact of pharmacological treatments for gestational diabetes on neonatal anthropometry independent of maternal glycaemic control: A systematic review and meta-analysis (PLoS Medicine)Maternal cardiovas...
Source: Browsing - Category: Databases & Libraries Tags: midwifery Source Type: blogs
ConclusionThe majority of this study cohort had back pain of benign cause. Some red flags were associated with greater risk of serious pathology, others were not. Further evidence regarding red flags and their association with serious pathology is required, to better inform clinical guidelines.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
In this study, we present three cases of testicular infarction and discuss their clinical characteristics, imaging features and clinical management. PATIENTS AND METHODS: Three adult males with prolonged epididymitis presented with chronic unilateral testicular pain, tenderness, and palpable swelling, including left varicocele in one case and hydrocele in the other two cases. Patient's symptoms were not relieved after antibiotic therapy. We analyzed the diagnosis, management, and outcome of these three cases of testicular infarction resulting from prolonged epididymitis. This includes the clinical characteristics, feat...
Source: Journal of X-Ray Science and Technology - Category: Radiology Tags: J Xray Sci Technol Source Type: research
We reported a54-year-old man with a complaint prolonged fever, abdominal pain, weight loss and lymphadenopathy without any immunosuppression who was eventually treated based on the diagnosis of diffuse tuberculosis. PMID: 32484114 [PubMed - as supplied by publisher]
Source: Infectious Disorders Drug Targets - Category: Infectious Diseases Authors: Tags: Infect Disord Drug Targets Source Type: research
NEW BRUNSWICK, NJ, May 27, 2020 — The Janssen Pharmaceutical Companies of Johnson &Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of SIRTURO® (bedaquiline). SIRTURO® is now indicated for use as part of combination therapy in the treatment of adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multidrug-resistant tuberculosis (MDR‑TB). In the U.S., the medicine should be reserved for use when an effective treatment regimen cannot otherwise be provided. This indication received accelera...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
The healing power of ultraviolet light (UV) has flown under the radar for decades. Yet, it’s one of the most powerful detoxifying agents known to man. It kills bacteria and viruses and can be used in a clinical setting. The therapeutic benefits of light have been known for millennia. Hippocrates, the father of modern medicine, believed light was essential to balance the body and emotions. And there is good reason why, during the Spanish flu pandemic of 1918, medics discovered that severely ill patients had hugely better recovery rates when they were nursed outside and had regular exposure to sunlight.1 You see, UV r...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Health Source Type: news
A 59-year-old woman with history of breast cancer and tuberculosis was referred to our hospital complaining of abdominal pain, distention and feeling feverish. A triphasic CT scan showed several cystic liver lesions, with a 110x72mm septate lesion in segments II-III with infiltrative morphology, as well as mediastinal and paraaortic lymph nodes(Image 1). A malignant etiology could not be ruled out.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
CONCLUSION: In the diagnosis process of patients with tuberculosis, it was determined that there was an improvement in the patient delay; however, the improvement in diagnosis delay was still not acceptable as an ideal duration. PMID: 32421283 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
Abstract The aim of review is to deal with management challenges related either to diagnosis or therapy of non-infectious pericarditis. In European countries with a low prevalence of tuberculosis, the aetiology search is essentially aimed at the exclusion of most common causes, that may require a specific therapy and are at increased risk of complications: systemic autoimmune or autoinflammatory conditions, post-cardiac injury syndrome (5-20%), neoplastic pericardial involvement (5-10%), tuberculosis (about 5% of cases), and rarely purulent in 38°C, subacute course, large pericardial effusion, cardiac tamponad...
Source: Polish Heart Journal - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research
We present the case of a young woman with a history of previously treated pleural and pulmonary tuberculosis referred to our hospital for chest pain and a single pleural nodule seen on plain chest films and chest CT. Cultures of inflammatory-type material obtained by US-guided fine-needle biopsy of the pleural lesion were positive for Mycobacterium tuberculosis complex. The diagnosis was a paradoxical reaction to antituberculosis treatment; after 6 more months of treatment, the pleural lesion and chest pain disappeared. PMID: 32381376 [PubMed - as supplied by publisher]
Source: Radiologia - Category: Radiology Authors: Tags: Radiologia Source Type: research
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