Alemtuzumab-induced thyroid events in multiple sclerosis: a systematic review and meta-analysis

ConclusionAmong different categories of ATEs, Graves ’ hyperthyroidism was the most common thyroid dysfunction, occurring in more than half of cases. Antithyroid drugs should represent the first-line treatment for ALZ-induced GD patients. However, alemtuzumab-induced GD could not be considered as having a more favourable outcome than conventional GD , given the substantial chance to encounter a fluctuating and unpredictable course.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research