The effect of oral melatonin on renal ischemia-reperfusion injury in transplant patients: A double-blind, randomized controlled trial.

CONCLUSIONS: Reduction in serum levels of renal function and oxidative stress/inflammatory markers in the melatonin group indicates that melatonin can inhibit IRI outcomes in RTPs through its anti-oxidant and anti-inflammatory properties. However, these properties do not appear as a result of influence on the level of Klotho gene/protein expression.
PMID: 31446153 [PubMed - as supplied by publisher]

Source: Transplant Immunology - August 21, 2019 Category: Transplant Surgery Authors: Panah F, Ghorbanihaghjo A, Argani H, Haiaty S, Rashtchizadeh N, Hosseini L, Dastmalchi S, Rezaeian R, Alirezaei A, Jabarpour M, Ahmad SNS, Sanajoo D Tags: Transpl Immunol Source Type: research