Comparable radiation response of ex vivo and in vivo irradiated tumor samples determined by residual γH2AX.

CONCLUSION: The ability of ex vivo irradiated tumor biopsies to reflect and predict the intrinsic radiation response of in vivo tumors increases the translational potential of the ex vivo γH2AX foci assay as a diagnostic tool for clinical practice.
PMID: 31445839 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - August 20, 2019 Category: Radiology Authors: Rassamegevanon T, Löck S, Baumann M, Krause M, von Neubeck C Tags: Radiother Oncol Source Type: research