Radiotherapy after skin-sparing mastectomy with immediate breast reconstruction in intermediate-risk breast cancer

ConclusionsFor intermediate-risk as well as early stage high-risk BC patients, the DEGRO Breast Cancer Expert Panel recommends the use of PMRT following SSME and NSME when a  10-year locoregional recurrence risk is likely to be greater than 10%, as estimated by clinical and biological risk factors. Subvolume-only radiation is discouraged outside of trials. The impact of adequate systemic treatment and the value of radiotherapy on optimal locoregional tumor control, wit h the goal of less than 5% LRR at 10-years follow-up, has to be verified in prospective trials.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research