Negative association between serum adropin and hypertensive disorders complicating pregnancy.

Negative association between serum adropin and hypertensive disorders complicating pregnancy. Hypertens Pregnancy. 2019 Aug 23;:1-8 Authors: Lin D, Yong J, Ni S, Ou W, Tan X Abstract Objective: Study the association of adropin and hypertensive disorders complicating pregnancy (HDCP). Methods: Patients with HDCP were matched with normotensive women (47 pairs). Adropin concentrations were detected by enzyme-linked immunosorbent assay. Results: Compared with the controls, the serum adropin levels were lower in the HDCP group (P
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research

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In this study we were interested in examining the number of patients developing preeclampsia with severe features at term. We also investigated whether factors at admission might be predictive of disease progression.We performed a retrospective cohort study at a tertiary obstetric hospital in Melbourne, Australia from 2015 to 2017. There were 124 participants presenting with preeclampsia at term and included in our study. After admission, 44.4% progressed to preeclampsia with severe features. Disease features at admission associated with disease progression were chronic hypertension, elevated systolic blood pressure, reduc...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
ConclusionThe yearly number of publications on pre-eclampsia has substantially increased, with a stable number of high-level study types and publications from high-impact journals. The reporting quality and usefulness of RCTs relating to pre-eclampsia have improved over time.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Conclusion: In healthy pregnancy, we reported CIMT was related to BMI and maternal age but not parity or gestational age. PMID: 31535936 [PubMed - as supplied by publisher]
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research
Conclusions: Mature ovarian teratoma, uterine fibroids and pregestational hypothyroidism may also contribute to the incidence of preeclampsia. PMID: 31530202 [PubMed - as supplied by publisher]
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research
Objectives: Either maternal gestational diabetes mellitus (GDM) or hypertensive disorder of pregnancy (HDP) is associated with an increased risk of obesity in the offspring. However, their joint associations with obesity in offspring remain unclear. We investigated the joint associations of maternal GDM and HDP with childhood overweight in offspring.Methods: We performed a large study in 1967 mother-child pairs. Maternal GDM was diagnosed according to the 1999 World Health Organization (WHO) criteria. HDP was defined as self-reported doctor-diagnosed hypertension or treatment of hypertension (including gestational hyperten...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Publication date: October 2019Source: Pregnancy Hypertension, Volume 18Author(s): Sandra S. Reyes-Aguilar, Irais Poblete-Naredo, Yury Rodríguez-Yáñez, Rogelio O. Corona-Núñez, Christian D. Ortiz-Robles, Emma S. Calderón-Aranda, Arnulfo AlboresAbstractThe impact of pregnancy hypertension in the offspring endothelia remains unknown. We evaluated the transcriptional expression of four genes that participate in the process of endothelial dysfunction using umbilical vein endothelial cell cultures (HUVEC) from healthy pregnant women (PW) and those with hypertensive disorders (HD). The cy...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
In this study, we investigated whether parental hypertension induces autonomic dysfunction in male adult offspring, and the H2S mechanism underlying this autonomic dysfunction. 2-kidney-1-clip method was employed to induce parental hypertension during pregnancy and lactation in rats. Basal blood pressure (BP) and autonomic function of male offspring in adulthood was evaluated. Additionally, either maternal hypertensive dams or their male offspring after weaning were treated with H2S to determine improving effects of H2S on autonomic dysfunction. The BP was significantly increased in male offspring of renovascular hypertens...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Hypertension is a common clinical complication in pregnancy, representing possible short-term and long-term risks of complications for both mothers and babies. Even if in a majority of cases hypertension is essential, possible secondary causes, which can be related to endocrine disorders, must be detected and correctly managed. This review focuses on the evaluation and the management of primary hyperaldosteronism, Cushing syndrome, and pheochromocytoma in pregnancy.
Source: Endocrinology and Metabolism Clinics of North America - Category: Endocrinology Authors: Source Type: research
Abstract BACKGROUND: The hypertensive disorders of pregnancy include pre-eclampsia, gestational hypertension, chronic hypertension, and undefined hypertension. Pre-eclampsia is considerably more prevalent in low-income than in high-income countries. One possible explanation for this discrepancy is dietary differences, particularly calcium deficiency. Calcium supplementation in the second half of pregnancy reduces the serious consequences of pre-eclampsia, but has limited effect on the overall risk of pre-eclampsia. It is important to establish whether calcium supplementation before, and in early pregnancy (before ...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
We examined the relationship between worry about pregnancy health and pre-eclampsia. General stress, mental health, and self-reported pregnancy health worry were measured in a study of 10,037 U.S. nulliparous women. Logistic regression found a dose-response relationship between first trimester pregnancy-health worry and subsequent pre-eclampsia onset, controlling for health history (Beta = 0.40, SE = 0.09, P 
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
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