Violet-Blue Light Arrays at 405nm Exert Enhanced Antimicrobial Activity for Photodisinfection of Monomicrobial Nosocomial Related Biofilms.

This study reports the efficacy of VBL and BL, and its antimicrobial activity against mature biofilms of a range of important nosocomial pathogens. Whilst this study investigates the antibacterial activity of a range of wavelengths between 375-450nm, and identifies a specific wavelength region (∼405nm) with increased antibacterial activity, decontamination was dependent on bacterial species, strain, irradiation parameters and experimental conditions. Further research with controlled experiments that ameliorate heating effects, and improve optical properties are required to optimise dosing parameters to advance successful clinical translation of this technology. PMID: 31444205 [PubMed - as supplied by publisher]
Source: Applied and Environmental Microbiology - Category: Microbiology Authors: Tags: Appl Environ Microbiol Source Type: research