Isolated primary cold abscess of the sternum: a case report

We present an unusual case of a large dumb-bell-shaped cold abscess arising due to infection of the sternum. A 23-year-old immunocompetent Asian woman presented with a gradually progressing painless swelling on anterior chest wall for the last 5  months. She had a large visible swelling on anterior chest wall which was 12.5 cm in diameter, soft, non-tender, temperature was not raised, and fluctuant. Magnetic resonance imaging showed a large dumb-bell-shaped hyperintense collection in upper anterior chest wall with marrow edema and corti cal irregularity in left side of manubrium. Pus was positive for nucleic acid testing (cartridge-based nucleic acid amplification test) forMycobacterium tuberculosis and later culture was also positive. She was started on anti-tubercular therapy and aspirated twice. Currently, she has completed 6  months of therapy and the swelling has now disappeared.DiscussionSwelling, pain localized to sternum, or ulceration of the skin with discharging sinus along with or without constitutional symptoms are the usual presentation. A high element of suspicion is needed for early diagnosis and treatment to prevent its complications. Sternal mycobacterial infections are categorized as primary, secondary, and/or acquired postoperatively. Although radiological investigations aid in diagnosis, the diagnosis is established by positive culture or histopathological examination. Anti-tubercular therapy is the mainstay of treatment with standard ...
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research

Related Links:

I was hoping to post this on the...forum that doesn't exist...but still awaiting access. If you don't feel comfortable posting a reply on the general forum I'd really appreciate a DM. Thanks in advance... So I have an offer to work with an ortho group and wonder if I can get some insight from all you wise folks on how to fairly counter what I think is a pretty poor offer... The good: Practice is in a part of town with an excellent payor mix. It's 3 orthos who have broken off from a... What do you all think of this offer to join an ortho group...
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
wanted to see groups timeline from MBB to RFA after its decided that its axial pain requiring RFA- how you guys do the follow ups after the procedures? does it take 6-8 weeks to go from first MBB to final RFA
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
HEART attack symptoms include difficulty breathing, chest pain, and an overwhelming feeling of anxiety. But you could also be at risk of a deadly myocardial infarction and heart disease symptoms if you develop this sign on your skin. Has your skin changed colour?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
The use of oral corticosteroids and reduced weight bearing in Duchenne muscular dystrophy (DMD) increases risk of poor bone health, resulting in osteoporosis, bone pain, fractures and vertebral deformities. We carried out a retrospective study within Birmingham Heartlands Hospital's Paediatrics Department, one of our largest referral centres for Neuromuscular
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
In Pompe disease (glycogen storage disease type II), the lysosomal α-glucosidase deficiency leads to pathological glycogen accumulation in muscle, but also in other tissues such as the peripheral nervous system. Since chronic pain has been reported in late onset Pompe disease (LOPD), we aimed to investigate the pain characteristics and whether small fiber affectio n may play a role in the mediation of pain. 32 patients with LOPD under enzyme replacement therapy (56% females; age 52.8 ±13.5 years, with duration from Pompe symptom onset 15.94± 10.19 years) were enrolled.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
Titin related disorder is an emerging genetic disorder that is not well described. New phenotypes are being described with improvement in diagnostic genetic testing. We are presenting a 16-year-old Indian boy with congenital static myopathy, complete ophthalmoplegia, thoracolumbar scoliosis and obstructive sleep apnea. His investigations were significant for abnormal muscle magnetic resonance imaging with severe involvement of the gluteal, anterior compartment muscle and clear adductor sparing. His muscle biopsy of right vastus lateralis showed multi-minicores and distinctive cap-like structures.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
The degree of muscle replacement by fat, as determined from fat fraction (FF) maps using quantitative nuclear magnetic resonance imaging (NMRI), is a marker of ‘disease progression’ and has an integrative character. More predictive NMR biomarkers, reflecting rather the ‘disease activity’, such as water T2 and phosphorus (31P) NMR spectroscopy indices have proven their value in different neuromuscular disorders. Here, we investigated the correlation between the FF and FF changes over three years (ΔFF) and different 31P NMRS indices, including the level of phosphodiesters (PDE), normalized over ...
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
In this study, we assesse d the fat fraction (FF) and fat fraction changes ΔFF over three years, as well as the correlation between water T2 and ΔFF, in 7 leg and 9 thigh muscles (and the weighted global values in leg and thigh), in 54 patients from the Jain Foundation's COS for dysferlinopathy from two different locations (Newcastle University and Institute of Myology, Paris) obtained annually over 3 years.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
Myotonic dystrophy type 1 (DM1) is characterized by structural changes affecting skeletal muscle tissue, resulting in progressive muscle dysfunction and wasting. Quantitative biomarkers are needed to monitor disease progression and to assess treatment efficacy of upcoming innovative therapeutics. Magnetic resonance imaging (MRI) can provide useful insight for biomarkers since intramuscular fat fraction (FF), as measured by Dixon and water T2 (T2H2O) are considered efficient biomarkers of disease severity and disease activity of various neuromuscular diseases (NMDs) respectively.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
Gastro-intestinal disorders in myotonic dystrophy type 1 (DM1) are poorly understood and often overlooked by the medical community. The aim of this study is to describe gastro-intestinal manifestations of DM1 patients, to assess the impact on quality of life (GIQLI scale) and to identify factors associated. Thirty-two patients were included. Fifty percent reported digestive troubles. Abdominal pain and diarrhea were the most frequently reported ones (62% and 81% respectively). We did not find any factor linked to the presence of these disorders: (i) the duration of progression of the pathology, (ii) the level of CTG expans...
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
More News: Back Pain | Databases & Libraries | Endemics | General Medicine | MRI Scan | Osteomyelitis | Pain | Skin | Tuberculosis