Scanned Proton Beam Performance and Calibration of the Shanghai Advanced Proton Therapy Facility

Publication date: Available online 24 August 2019Source: MethodsXAuthor(s): Hang Shu, Chongxian Yin, Haiyang Zhang, Ming Liu, Manzhou Zhang, Liying Zhao, Kecheng Chu, Xiaolei Dai, Michael F. MoyersAbstractThe Shanghai Advanced Proton Therapy facility (SAPT) is a hospital-based facility that began construction in December of 2014 with commissioning of the first scanned proton beam line starting in October of 2017. Proton beams are extracted from a synchrotron accelerator with energies between 70 and 235 MeV. Beam delivery uses the modulated scanning and energy stacking techniques to produce a maximal scanning area of 40 × 30 cm2 at the iso-center. Prior to clinical use, the beam delivery system was characterized and calibrated following the guidelines of the IEC 62667 medical electronic equipment standard including the spot size in air, spot position, depth dose distributions, and lateral dose profiles, as well as the beam monitor calibrations following the IAEA TRS-398 recommendations with small differences.•The measured dosimetric results showed that the full width at half maximum (FWHM) for the beam spot size in air varied approximately from 6 mm to 13 mm. The dose fall-off (DDF) derived from the measured depth dose in water varied from 4.7 mm at 235 MeV to 0.7 mm at 70 MeV. The homogeneity of the scanned field was better than 2% for various energies as expected.•Furthermore, the beam reproducibi...
Source: MethodsX - Category: Science Source Type: research

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Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
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Source: The British Journal of Radiology - Category: Radiology Authors: Tags: Br J Radiol Source Type: research
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Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
Abstract We developed a synchrotron-based real-time-image gated-spot-scanning proton-beam therapy (RGPT) system and utilized it to clinically operate on moving tumors in the liver, pancreas, lung, and prostate. When the spot-scanning technique is linked to gating, the beam delivery time with gating can increase, compared to that without gating. We aim to clarify whether the total treatment process can be performed within approximately 30 min (the general time per session in several proton therapy facilities), even for gated-spot-scanning proton-beam delivery with implanted fiducial markers. Data from 152 pati...
Source: Journal of Applied Clinical Medical Physics - Category: Physics Authors: Tags: J Appl Clin Med Phys Source Type: research
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Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
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Source: The British Journal of Radiology - Category: Radiology Authors: Tags: Br J Radiol Source Type: research
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Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
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Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
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