Persistent C-peptide secretion in Type 1 diabetes and its relationship to the genetic architecture of diabetes

The objective of this cross-sectional study was to explore the relationship of detectable C-peptide secretion in type 1 diabetes to clinical features and to the genetic architecture of diabetes.
Source: BMC Medicine - Category: Internal Medicine Authors: Tags: Research article Source Type: research

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Dental caries and type 1 diabetes are responsible for a large burden of global disease; however, the exact prevalence of dental caries among children and adolescents with type 1 diabetes remains controversial,...
Source: BMC Oral Health - Category: Dentistry Authors: Tags: Research article Source Type: research
Immune analytes have been widely tested in efforts to understand the heterogeneity of disease progression, risk, and therapeutic responses in type 1 diabetes (T1D). The future clinical utility of such analytes as biomarkers depends on their technical and biological variability, as well as their correlation with clinical outcomes. To assess the variability of a panel of 91 immune analytes, we conducted a prospective study of adults with T1D (
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conditions:   Diabetes Mellitus, Type 1;   Insulin Hypoglycemia Interventions:   Behavioral: " Five sessions per period " - " Two sessions per period " ;   Behavioral: " Two sessions per period " - " Five sessions per period " Sponsor:   Steno Diabetes Center Copenhagen Recruiting
Source: - Category: Research Source Type: clinical trials
Authors: Papanas N, Pafili K, Demetriou M, Chatzikosma G, Papachristou S, Papazoglou D PMID: 31509155 [PubMed - in process]
Source: Review of Diabetic Studies - Category: Endocrinology Tags: Rev Diabet Stud Source Type: research
This study is designed to develop a Chinese version of the Diabetes Strengths and Resilience Measure for Adolescents (DSTAR-Teen) and evaluate its psychometric characteristics.
Source: Journal of Pediatric Nursing - Category: Nursing Authors: Source Type: research
Conclusion: Good2Go is a valid 20-item questionnaire to assess transition readiness in adolescents with chronic conditions and may be useful in routine care to propose individually tailored preparation for their transfer to adult healthcare. Further research is now needed to analyze correlation between domain scores and success of transition.What is Known:•In adolescents with chronic conditions, the use of transition readiness questionnaires is recommended to propose individually tailored preparation for their transfer to adult healthcare.•However, no French-language questionnaire has been so far validated.What i...
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
AbstractLittle is known about the human islet life span, and beta-cell neogenesis is generally considered rare in adults. However, based on available data on beta-cell proliferation, calculations can be made suggesting that the dynamics of the endocrine pancreas is considerable even during adulthood, with islet neogenesis and a sustained increase in size of already formed islets. Islet-associated hemorrhages, frequently observed in most mammals including humans, could account for a considerable loss of islet parenchyma balancing the constant beta-cell proliferation. Notably, in subjects with type 1 diabetes, periductal acc...
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
DiabetesMine explores the risks and benefits of exercise for those living with type 1 diabetes.
Source: Diabetes Mine - Category: Endocrinology Authors: Source Type: blogs
Resveratrol and resveratrol-hydroxypropyl-β-cyclodextrin complex recovered the changes of creatine kinase and Na+, K+-ATPase activities found in the spleen from streptozotocin-induced diabetic rats. An Acad Bras Cienc. 2019;91(3):e20181330 Authors: Kolling J, Kolling J, Franceschi ID, Nishihira VSK, Baldissera MD, Pinto CG, Mezzomo NJ, Carmo GMD, Feksa LR, Fernandes LS, Orengo G, Vaucher RA, Giongo JL, Wyse ATS, Wannmacher CMD, Rech VC Abstract Type 1 diabetes (T1D) is the result of the selective destruction of the pancreatic β-cells by T cells of the immune system. Although spleen is a seco...
Source: An Acad Bras Cienc - Category: Science Authors: Tags: An Acad Bras Cienc Source Type: research
Hurricane Dorian’s 185 mph winds and punishingly slow pace smashed entire neighborhoods in the Bahamas, killing at least 50 people. But now, Bahamians are facing a different kind of threat. The lack of access to toilets, clean water and medications puts tens of thousands at risk for disease, public health experts warn. Bahamians in the hardest-hit areas are already suffering from cuts and gashes caused by widespread debris and wreckage. But now aid groups are saying survivors are beginning to show signs of gastrointestinal issues from contaminated water. Those with chronic illnesses are struggling without access to t...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Bahamas Infectious Disease onetime weather Source Type: news
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