A new therapeutic strategy with istradefylline for postural deformities in Parkinson's disease.

CONCLUSIONS AND CLINICAL IMPLICATIONS: Postural deformities caused by dopamine agonists generally improve less than two weeks after dopamine agonist withdrawal. Given the response time in the present study, the response was unlikely to be caused solely by dopamine agonist withdrawal. Istradefylline can be a potential therapeutic option; however, appropriate selection of patients for treatment with istradefylline is warranted.
PMID: 31441493 [PubMed - as supplied by publisher]

Source: Neurologia i Neurochirurgia Polska - August 22, 2019 Category: Neurology Authors: Fujioka S, Yoshida R, Nose K, Hayashi Y, Mishima T, Fukae J, Kitano K, Kikuchi H, Tsuboi Y Tags: Neurol Neurochir Pol Source Type: research