Multiple sclerosis: oral health, behaviours and limitations of daily oral hygiene - a questionnaire study.
CONCLUSIONS AND CLINICAL IMPLICATIONS: Dry mouth and bleeding from gums are more frequent in patients with longer lasting and more advanced types of MS. Daily oral hygiene and oral health self-control is limited in patients with MS, mainly due to motor deficits, balance problems and pain, and this becomes worse with disease duration. To minimise the burden of the disease, patients with MS require better education and improvement in their awareness regarding proper oral health control, such as the use of electric toothbrushes. In addition, patients with chronic and progressive disability from multiple sclerosis may benefit from better organised access to dental care. PMID: 31441495 [PubMed - as supplied by publisher]
ConclusionsChildhood utilities derived from children or proxies are not interchangeable. The choice of self or proxy assessor may have potentially significant implications for economic evaluations of child health interventions.
Discussion/conclusionThe study hypothesis was confirmed: there were no differences according to primary versus secondary osteoarthritis in preoperative profile or results. Elbow osteoarthritis entails mechanical impingement. Arthroscopic debridement gave good results independently of primary or post-traumatic etiology.Level of evidenceIII, prospective comparative observational multicenter cohort study.
ConclusionWater vapor endometrial ablation preserved an accessible uterine cavity and visualization of the ostia in the majority of subjects, with minimal incidence of severe adhesions a mean of four years following the ablation procedure.
Authors: Andrade RR, Oliveira-Neto OB, Barbosa LT, Santos IO, Sousa-Rodrigues CF, Barbosa FT Abstract BACKGROUND AND OBJECTIVES: Low back pain is a prevalent disease in the adult population, whose quality of life is considerably affected. In order to solve this problem, several therapies have been developed, of which ozone therapy is an example. Our objective in this study was to determine the effectiveness of ozone therapy for lumbar pain relief in adult patients compared to other therapies (steroid and placebo). METHOD: We usused randomized clinical trials to compare the effectiveness of ozone and other thera...
ConclusionsEmotion dysregulation is associated with symptoms of depression and anxiety in PwMS. Given the malleability of this construct, this study underscores the importance of further investigating emotion dysregulation, and possibly adopting it as a surrogate endpoint in interventions targeting affective disorders in PwMS.
ConclusionsThe immuno-regulatory functions of B cells were significantly impaired whereas TFH cells were markedly increased in the acute phase of MOG-antibody-associated demyelination. Despite having distinct clinical features, MOG-antibody-associated demyelination shared a similar lymphocytic profile with AQP4-antibody-positive NMOSD in the acute relapse phase.
Publication date: Available online 16 September 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): Sofia Oliveira, Renato Oliveira
Back in May, Bruce Schoneboom wrapped up his appointment to the HHS Pain Management Best Practices Inter-Agency Task Force. The group determined best practices for managing chronic and acute pain—and addressed judicious prescribing of opioids. If you didn’t know: The CDC reports there are 192 overdose deaths in the U.S. every day. Forty percent of The post Dr. Bruce Schoneboom and the HHS Pain Task Force appeared first on Johns Hopkins Nursing Magazine.
This study is registered with ClinicalTrials.gov, number NCT02400463, and is still recruiting.FindingsAs of Feb 7, 2019, five patients had been enrolled. The first patient was enrolled in February, 2016. No deaths were recorded, with a median follow-up of 490 days (IQR 190–1075). 2-month overall survival was 100% (95% CI 57–100). Regarding response, resolution of symptoms (either partial or complete) and disease-associated laboratory abnormalities was observed in all five patients. Cytopenias improved in all patients within the first week of treatment, leading to relatively rapid transfusion independence, disco...
Authors: Dyga K Abstract The article was written with the intention of filling the gap in the Polish psychiatric literature, which has not yet found room for the analysis of the phenomenon of bipolar disorder (BD) in terms of consequences that it may have for identity of people diagnosed with it. In order to do that, taking into account absence of the research in Poland, an attempt was made to find all previous reports on this subject in English-language professional journals and monographs. As a result, a detailed description with commentaries was made on five thorough studies of essentially qualitative nature. Al...