Rapid suppression of bone formation marker in response to sleep restriction and circadian disruption in men

ConclusionSleep restriction with concurrent circadian disruption induced a relatively rapid decline in P1NP (despite no change in CTX) and levels remained lower with ongoing exposure. These data suggest (1) even brief sleep restriction and circadian disruption can adversely affect bone metabolism, and (2) there is no P1NP recovery with ongoing exposure that, taken together, could lead to lower bone density over time.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research