Plaque calcification is driven by different mechanisms of mineralization associated with specific cardiovascular risk factors

ConclusionOur results support the hypothesis that the process of atherosclerotic plaque calcification presents a number of similarities with the physiological processes that occur in bone, involving both osteoblasts- and osteoclasts-like arterial cells. Finally, the present study suggests that risk factors, such as hypertension, cigarette smoke and diabetes, can cause the destabilization of the atheromatic plaque acting on calcification process as well as inflammation.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research