Effects of salinomycin and niclosamide on small cell lung cancer and small cell lung cancer circulating tumor cell lines

In conclusion, the SCLC CTCs established from patients with relapsed disease lack a typical CSC phenotype in respect to chemosensitivity to CSC-selective drugs, surface markers, expression of pluripotent stem cell and transcription factors.

http://link.springer.com/10.1007/s10637-019-00847-8

Source: Investigational New Drugs - August 23, 2019 Category: Drugs & Pharmacology Source Type: research