Elevated luteinizing hormone contributes to atherosclerosis formation by inhibiting nitric oxide synthesis via PI3K/Akt pathway.

CONCLUSIONS: Elevated LH promotes atherosclerosis formation in OVX ApoE-/- female mice. This effect may be mediated by inhibiting endothelial NO synthesis via PI3K/Akt signaling pathway. PMID: 31437529 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31437529?dopt=Abstract

Source: Vascular Pharmacology - August 18, 2019 Category: Drugs & Pharmacology Authors: Meng X, Li X, Xu X, Li P, Chen Y, Fu X, Xu X Tags: Vascul Pharmacol Source Type: research