Viruses, Vol. 11, Pages 780: Pulmonary Involvement during the Ebola Virus Disease
Viruses, Vol. 11, Pages 780: Pulmonary Involvement during the Ebola Virus Disease
Viruses doi: 10.3390/v11090780
Authors:
Eleonora Lalle
Mirella Biava
Emanuele Nicastri
Francesca Colavita
Antonino Di Caro
Francesco Vairo
Simone Lanini
Concetta Castilletti
Martin Langer
Alimuddin Zumla
Gary Kobinger
Maria R. Capobianchi
Giuseppe Ippolito
Filoviruses have become a worldwide public health concern, especially during the 2013–2016 Western Africa Ebola virus disease (EVD) outbreak—the largest outbreak, both by number of cases and geographical extension, recorded so far in medical history. EVD is associated with pathologies in several organs, including the liver, kidney, and lung. During the 2013–2016 Western Africa outbreak, Ebola virus (EBOV) was detected in the lung of infected patients suggesting a role in lung pathogenesis. However, little is known about lung pathogenesis and the controversial issue of aerosol transmission in EVD. This review highlights the pulmonary involvement in EVD, with a special focus on the new data emerging from the 2013–2016 Ebola outbreak.
Source: Viruses - Category: Virology Authors: Eleonora Lalle Mirella Biava Emanuele Nicastri Francesca Colavita Antonino Di Caro Francesco Vairo Simone Lanini Concetta Castilletti Martin Langer Alimuddin Zumla Gary Kobinger Maria R. Capobianchi Giuseppe Ippolito Tags: Review Source Type: research
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